DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8159 and CG10274

DIOPT Version :9

Sequence 1:NP_649823.2 Gene:CG8159 / 41040 FlyBaseID:FBgn0037619 Length:399 Species:Drosophila melanogaster
Sequence 2:NP_001097525.1 Gene:CG10274 / 38716 FlyBaseID:FBgn0035690 Length:863 Species:Drosophila melanogaster


Alignment Length:596 Identity:108/596 - (18%)
Similarity:182/596 - (30%) Gaps:224/596 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 VCRVCAS----STDNSKSLKLF-NSGACKVLQQINLLTGVLLQCEPGLPDWMCETCQTDLKSAIS 64
            |||:|.:    :...:.|..|| ..|..|   ::.:.|.:.::...|.|..:|..|.:.|.....
  Fly    15 VCRICLNRLPENGGGAGSFDLFLIPGLAK---KLCVCTSLAVEQSDGFPKCLCAQCFSRLDDMHE 76

  Fly    65 FRDRCLRSQKIFEE-------------------------------------------------SL 80
            |:..|:.|.:.|::                                                 .:
  Fly    77 FQKLCVDSVQKFQDMVARNVFCPPASAQMKNFDLLNVAGNEPELVGQDEEDRINFDPLLDHKMEM 141

  Fly    81 VRNEEDTFRSSVRRSARSQRQRHEDTAPKTPASPLEVMIKLESLSNGDEE-DDGIDHLDSCNEAD 144
            :.||||.|:........:::...|....:..|:.|..:...||....:|: |..:|...:.::.|
  Fly   142 IENEEDVFKMLEHVDKEAEQVEKEVKQDELDAADLMTIFAAESSEESEEDIDQDVDFEPNSSDGD 206

  Fly   145 MELAI--------------KAM------------SSSTEDDGTTSPVRLKR-------------- 169
            .::.:              ||.            |...::||..|..|.||              
  Fly   207 DDVPLAQRLRDNSRMIPKAKAAVIKEEDQEFPTGSEEEDEDGEKSKSRRKRIPPGERHLHRIIDC 271

  Fly   170 -------------------------------TRRRGLKKGG------------------------ 179
                                           |.|:|....|                        
  Fly   272 HICHQKFKKAIRYEEHMKHHNDLLPFQCKVETCRKGFTTAGGLRLHIDHAHTELSEVHSCNVDGC 336

  Fly   180 ---------------KGENRTKVTLPV--FFCDQCGNNITGKSSFDRHLRKHSGIR-PFQCELCP 226
                           |....||...|.  :.|.:|........:..:|:.||.|.. ||.|.:|.
  Fly   337 GKTFPRIRLLTFHMKKMHGITKAAAPPRDYPCTECEKVFRCPMALKKHMYKHDGKELPFPCNICG 401

  Fly   227 ARFLSSGELKGHQVMHTG----------------------------DRKFQCRYCDRTYVNYSGR 263
            .||:.:..||.|.:.|.|                            ::||:|..|:....|....
  Fly   402 KRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHILTHTQEKKFKCHICEHASHNKQSL 466

  Fly   264 LRHER-THTNDRPFICAQCGKSFTNSYILKNHMLIHTGERLFRCELCHRSFARP----THLKTHF 323
            ..|.: .|...:.:.|..|||:|..|:..|.|.:.||||:...|::|.:.|..|    .|||||.
  Fly   467 ANHIKIVHEKIKNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYPKSLTKHLKTHE 531

  Fly   324 RS-----NTHKHNLEKSMADAGGVQLSPSQSADQVKFVTEKEPEAEADAFTIEVPLPAEQEQDES 383
            :.     .|::.. :..|.:..|.|.             :..|....:..:|| |:.:....||.
  Fly   532 KRVLRAIETYRQR-QVEMGETPGEQF-------------DNPPAPPVEGISIE-PIMSRNAADEL 581

  Fly   384 LGLAALETSTL 394
            |.:.|...:|:
  Fly   582 LKVCAESVATI 592

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8159NP_649823.2 zf-AD 5..78 CDD:214871 19/77 (25%)
C2H2 Zn finger 194..214 CDD:275368 3/19 (16%)
COG5048 <197..322 CDD:227381 42/158 (27%)
zf-H2C2_2 206..231 CDD:290200 10/25 (40%)
C2H2 Zn finger 222..242 CDD:275368 7/19 (37%)
C2H2 Zn finger 250..270 CDD:275368 4/20 (20%)
zf-H2C2_2 265..287 CDD:290200 7/22 (32%)
C2H2 Zn finger 278..298 CDD:275368 8/19 (42%)
zf-H2C2_2 291..315 CDD:290200 9/23 (39%)
C2H2 Zn finger 306..328 CDD:275368 9/30 (30%)
CG10274NP_001097525.1 zf-AD 15..90 CDD:214871 19/77 (25%)
C2H2 Zn finger 334..353 CDD:275368 0/18 (0%)
C2H2 Zn finger 368..388 CDD:275368 3/19 (16%)
COG5048 394..729 CDD:227381 52/214 (24%)
C2H2 Zn finger 397..417 CDD:275368 7/19 (37%)
C2H2 Zn finger 425..445 CDD:275368 0/19 (0%)
C2H2 Zn finger 453..474 CDD:275368 4/20 (20%)
C2H2 Zn finger 482..502 CDD:275368 8/19 (42%)
C2H2 Zn finger 510..530 CDD:275368 7/19 (37%)
C2H2 Zn finger 638..659 CDD:275368
C2H2 Zn finger 667..687 CDD:275368
zf-H2C2_2 680..704 CDD:290200
C2H2 Zn finger 695..715 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24388
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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