DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8159 and M03D4.4

DIOPT Version :9

Sequence 1:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001023313.1	Gene:	M03D4.4 / 177375	WormBaseID:	WBGene00019751	Length:	505	Species:	Caenorhabditis elegans

Alignment Length:	271	Identity:	72/271 - (26%)
Similarity:	112/271 - (41%)	Gaps:	46/271 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 RSQRQRHEDTAPKTPASPLEVMIKLESLSNGDEEDDGIDHLDSCNEADMELAIKAMSSSTEDDGT 161
            |.:|:.|                  |::..||:|:|.::  |..:|..| :.||...|....|..
Worm    22 RHEREEH------------------ETVEQGDQEEDRME--DDSDELAM-IKIKIEDSDFLSDTD 65

  Fly   162 TSPVRLKRTRRRGLKKGGKGENRTKVTLPVFFCDQCGNNITGKSSFDRHLRKHSGIRPFQCELCP 226
            :|.:.:..|...  :|...||...      :.|:.|......|.....|:|.|||.:|..|..|.
Worm    66 SSQLSMNPTTPS--EKSSSGEKGR------YECEDCHEMFAVKRELATHMRIHSGEQPHSCTQCG 122

  Fly   227 ARFLSSGELKGHQVMHTGDRKFQCRYCDRTYVNYSGRLRHERTHTNDRPFICAQCGKSFTNSYIL 291
            ..|.:...||.|.:.|||:|...|.:|::.:.......:|...|:..||..|.||.|:|...:.|
Worm   123 KEFGTRQLLKKHWMWHTGERSHVCPHCNKAFFQKGHLTQHLMIHSGGRPHECPQCHKTFIFKFDL 187

  Fly   292 KNHMLIHTGERLFRCELCHRSFARPT-----HLKTHFRSNTHKHNLEKSMADAGGVQLSPSQSAD 351
            ..||.||. ||.|.|:.|.|||.:..     |||...:.::...:|           |:|:..|.
Worm   188 NRHMKIHQ-ERGFSCQQCGRSFLKQVMLDEHHLKCKGKPSSPIRSL-----------LTPTMKAG 240

  Fly   352 QVKFVTEKEPE 362
            ....::.|.|:
Worm   241 LESAISIKPPQ 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871
		C2H2 Zn finger	194..214	CDD:275368	5/19 (26%)
		COG5048	<197..322	CDD:227381	45/129 (35%)
		zf-H2C2_2	206..231	CDD:290200	9/24 (38%)
		C2H2 Zn finger	222..242	CDD:275368	6/19 (32%)
		C2H2 Zn finger	250..270	CDD:275368	3/19 (16%)
		zf-H2C2_2	265..287	CDD:290200	9/21 (43%)
		C2H2 Zn finger	278..298	CDD:275368	8/19 (42%)
		zf-H2C2_2	291..315	CDD:290200	13/23 (57%)
		C2H2 Zn finger	306..328	CDD:275368	8/26 (31%)
M03D4.4	NP_001023313.1	C2H2 Zn finger	90..110	CDD:275368	5/19 (26%)
		zf-H2C2_2	102..127	CDD:290200	9/24 (38%)
		C2H2 Zn finger	118..138	CDD:275368	6/19 (32%)
		C2H2 Zn finger	146..166	CDD:275368	3/19 (16%)
		zf-H2C2_2	158..181	CDD:290200	8/22 (36%)
		zf-C2H2	172..194	CDD:278523	8/21 (38%)
		C2H2 Zn finger	174..194	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000