DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment nom and TT1

DIOPT Version :9

Sequence 1:NP_001262384.1 Gene:nom / 41038 FlyBaseID:FBgn0037617 Length:370 Species:Drosophila melanogaster
Sequence 2:NP_174737.2 Gene:TT1 / 840386 AraportID:AT1G34790 Length:303 Species:Arabidopsis thaliana


Alignment Length:270 Identity:53/270 - (19%)
Similarity:78/270 - (28%) Gaps:94/270 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 PLLQSDKVGASEEKKVEPND----------------PSTKKKTTKRRRGRPRMPLEIVDIVVTNE 126
            ||...:  |..||::.|..|                ||...|..|:|.|:        :|...:.
plant    63 PLYAEE--GEQEEEEEEEEDREVDVDLHIGLPGFGKPSNDAKQLKKRNGK--------EIATYDA 117

  Fly   127 SKASAGESVGGDEFDQPVEISNEPDATDSDVNLEEIDLPDEDGLESDHDLPNVQIHKCDTCGIIK 191
            .|....|..|...:                     |..|::..:...|       ..|..|....
plant   118 GKGIENELSGKAYW---------------------IPAPEQILIGFTH-------FSCHVCFKTF 154

  Fly   192 NNKSSLVRHQFEH-----------NGIRP-----YPCKECPKTFLVASELKAHNLTHHTLEPPFA 240
            |..::|..|.:.|           .|.:|     .||..|.:        ...|...|....|..
plant   155 NRYNNLQMHMWGHGSQYRKGPESLKGTQPRAMLGIPCYCCVE--------GCRNHIDHPRSKPLK 211

  Fly   241 CRYCDRRYFSVVGRKKHERVHTNERPFVCDQCGKAFTRTCILKAHMAVHQ--VVRKYSCDVCDRS 303
                |.|......::||     ..:||.|..|||...    :|.....|:  ..:::.| ||...
plant   212 ----DFRTLQTHYKRKH-----GHKPFSCRLCGKLLA----VKGDWRTHEKNCGKRWVC-VCGSD 262

  Fly   304 FSLKKHLATH 313
            |..|:.|..|
plant   263 FKHKRSLKDH 272

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nomNP_001262384.1 zf-AD 5..76 CDD:214871
C2H2 Zn finger 184..204 CDD:275368 5/19 (26%)
C2H2 Zn finger 212..261 CDD:275368 9/48 (19%)
zf-H2C2_2 255..278 CDD:290200 8/22 (36%)
C2H2 Zn finger 269..289 CDD:275368 5/19 (26%)
zf-H2C2_2 282..305 CDD:290200 5/24 (21%)
C2H2 Zn finger 297..313 CDD:275368 6/15 (40%)
TT1NP_174737.2 C2H2 Zn finger 231..247 CDD:275368 5/19 (26%)
C2H2 Zn finger 257..274 CDD:275368 7/17 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 62 1.000 Inparanoid score I2531
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

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