DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nom and Zfp110

DIOPT Version :9

Sequence 1:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_001347505.1	Gene:	Zfp110 / 65020	MGIID:	1890378	Length:	832	Species:	Mus musculus

Alignment Length:	147	Identity:	52/147 - (35%)
Similarity:	70/147 - (47%)	Gaps:	9/147 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 VQIHK------CDTCGIIKNNKSSLVRHQFEHNGIRPYPCKECPKTFLVASELKAHNLTHHTLEP 237
            ::|||      |..||.:..|......|:..|.|.|||.|..|.|.|:.:|.|..| |..|:.|.
Mouse   679 IKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQH-LRIHSGER 742

  Fly   238 PFACRYCDRRYFSVVGRKKHERVHTNERPFVCDQCGKAFTRTCILKAHMAVHQVVRKYSCDVCDR 302
            ||.|..|.|.:.......:|.|.||..:|:.|::|||||.::..|..|...|...|.|.|..|.:
Mouse   743 PFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGK 807

  Fly   303 SFSLKKHLATHFISNTH 319
            :|:...||..|  ..||
Mouse   808 AFTQSSHLIGH--QKTH 822

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nom	NP_001262384.1	zf-AD	5..76	CDD:214871
		C2H2 Zn finger	184..204	CDD:275368	5/19 (26%)
		C2H2 Zn finger	212..261	CDD:275368	17/48 (35%)
		zf-H2C2_2	255..278	CDD:290200	11/22 (50%)
		C2H2 Zn finger	269..289	CDD:275368	8/19 (42%)
		zf-H2C2_2	282..305	CDD:290200	7/22 (32%)
		C2H2 Zn finger	297..313	CDD:275368	5/15 (33%)
Zfp110	NP_001347505.1	KRAB	18..77	CDD:214630
		SCAN	159..246	CDD:307924
		KRAB	283..324	CDD:307490
		C2H2 Zn finger	663..682	CDD:275370	0/2 (0%)
		C2H2 Zn finger	690..710	CDD:275368	5/19 (26%)
		zf-H2C2_2	702..727	CDD:316026	10/24 (42%)
		C2H2 Zn finger	718..738	CDD:275368	8/20 (40%)
		zf-H2C2_2	730..754	CDD:316026	10/24 (42%)
		C2H2 Zn finger	746..766	CDD:275368	5/19 (26%)
		zf-C2H2	772..794	CDD:306579	8/21 (38%)
		C2H2 Zn finger	774..794	CDD:275368	8/19 (42%)
		zf-H2C2_2	786..811	CDD:316026	8/24 (33%)
		C2H2 Zn finger	802..822	CDD:275368	6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000