DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nom and CG1792

DIOPT Version :9

Sequence 1:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	402	Identity:	108/402 - (26%)
Similarity:	167/402 - (41%)	Gaps:	88/402 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRVCGRSRLCPKAVELFKPGRQDILRRIQLITGILLQQIP--NAPDMVCFCCQTDLQSAMIFRRQ 68
            ||.||....|.....||:.....:|.:|:::||:.|...|  ..|..:|..|:.|||:|:.||.:
  Fly     6 CRTCGLFIFCSTPSNLFEEPNSVMLHQIEVLTGLFLLGGPGNELPPFICSPCELDLQTAIAFRER 70

  Fly    69 CILQQKKWVPLLQSDKVGASE---------EKKVEPNDPSTKKKTTKRRRGRPRMPLEIVDIVVT 124
            .|..||   .|.:|..:|.:|         ||:::..:..|:              :|::|::..
  Fly    71 VIRTQK---TLQESPNLGNAELIESFAVGVEKEIQYAEEVTE--------------IEVIDLLPE 118

  Fly   125 NESKASAGESVGGDEFDQPVEISNEPDATDSDVNLEEIDLPDEDGLESDHDLPNV---------- 179
            ....         :|.::|.||..:.:.....|..:|..|     ..|....|.|
  Fly   119 EHLL---------EETEEPYEICEQNEQPQVKVPAQEKKL-----RRSTKTTPTVFTSVKFADNS 169

  Fly   180 --------------------QIHK----CDTCGIIKNNKSSLVRHQFEHNGIRPYPCKECPKTFL 220
                                :..|    |:.||......|:...|...|.|::.:.|.:|.:.|.
  Fly   170 QATRTQWSRLTEDEVVALKRERRKRDCICEQCGRHFTCPSNFKLHLLRHTGVKSFACDQCSQQFY 234

  Fly   221 VASELKAHNLTH--HTLEPPFACRYCDRRYFSVVGRKKHERV-HTNERPFVCDQCGKAFTRTCIL 282
            .|:.|:.|...|  :.|   |.||||:..|.:..||.:|||: |||.:||.|.:|.|:|..:..|
  Fly   235 TATLLRRHQELHAGNAL---FQCRYCEATYSNASGRIQHERMRHTNVKPFTCKECNKSFAMSGKL 296

  Fly   283 KAHMAVHQVVRKYSCDVCDRSFSLKKHLATHFISNTHKRNAEAVTSSSEYMSMLSFESDETWSQG 347
            :.||..|..||.:.||.|..||..:.||.:|:.|..|     |.|||::.......|.|...|.|
  Fly   297 RTHMLSHTGVRAFHCDSCQVSFVRRSHLTSHYRSKGH-----AHTSSAQAALDNPVELDVKASNG 356

  Fly   348 TPLTTSIDEDLV 359
            .. |.:.||.|:
  Fly   357 MQ-TGAKDEALL 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nom	NP_001262384.1	zf-AD	5..76	CDD:214871	25/71 (35%)
		C2H2 Zn finger	184..204	CDD:275368	5/19 (26%)
		C2H2 Zn finger	212..261	CDD:275368	19/51 (37%)
		zf-H2C2_2	255..278	CDD:290200	12/23 (52%)
		C2H2 Zn finger	269..289	CDD:275368	7/19 (37%)
		zf-H2C2_2	282..305	CDD:290200	10/22 (45%)
		C2H2 Zn finger	297..313	CDD:275368	7/15 (47%)
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	26/76 (34%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		C2H2 Zn finger	226..243	CDD:275368	5/16 (31%)
		C2H2 Zn finger	254..275	CDD:275368	10/20 (50%)
		zf-C2H2	281..303	CDD:278523	8/21 (38%)
		C2H2 Zn finger	283..303	CDD:275368	7/19 (37%)
		zf-H2C2_2	296..320	CDD:290200	11/23 (48%)
		C2H2 Zn finger	311..329	CDD:275368	8/17 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447756
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890