DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nom and CG14667

DIOPT Version :9

Sequence 1:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster

Alignment Length:	377	Identity:	92/377 - (24%)
Similarity:	154/377 - (40%)	Gaps:	87/377 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LINVCRVCG-------RSRLCPKAVELFKPGRQDILRRIQLITGILLQQIPNAPDMVCFCCQTDL 59
            |.:|||:|.       |.|      .:|...|...|.:::||||:.|.:....|::||..|.::|
  Fly     3 LADVCRICANKIMGHQRDR------NIFIHMRGKYLGQLKLITGVELTRNQGLPEIVCERCFSEL 61

  Fly    60 QSAMIFRRQCILQQKKWVPLLQ--SDKVGASEEKKVEPNDPSTKKKTTKRRRGRPRMPLEIVDIV 122
            ..|..||.:||..||..:.:::  ||:.....|...||.|.                  :::|.
  Fly    62 DLATKFRERCIFSQKYLLDIIKKTSDQSTVHVELSSEPLDE------------------QLIDA- 107

  Fly   123 VTNESKASAGESVGGDEFDQPVEISNEPD-------ATDSDVNLEEIDLPDEDG----------- 169
                              || :|...:.|       ..:...:||||:|.|:..
  Fly   108 ------------------DQ-LETHYDDDQYVCYQGTKEEHQDLEEIELDDDPSAAVIAAAEAAA 153

  Fly   170 -LESDHDLPNVQIHK----------CDTCGIIKNNKSSLVRHQFEHNGIRP----YPCKECPKTF 219
             .....||...::.:          ||.||.:.::......|...|...|.    :||.|||:||
  Fly   154 EAAQQEDLQEQEMERAAKRRSNFFICDECGTLFHDAFLYTEHLNGHQNRRDMNQFFPCPECPQTF 218

  Fly   220 LVASELKAHNLTHHTLEPPFACRYCDRRYFSVVGRKKHERVHTNERPFVCDQCGKAFTRTCILKA 284
            ...:.||.|....|.:...|.|..|...:.|:..:.:|::.|.||||:.|.:||..|:....|:.
  Fly   219 NKKALLKQHRTQVHLINRRFQCTICHEAFASLGAKLRHDKAHKNERPYPCLECGMIFSSVSELQN 283

  Fly   285 HMAVH-QVVRKYSCDVCDRSFSLKKHLATHFISNTHKRNAEAVTSSSEYMSM 335
            |.:.| :.:||:.|:.|:..|..::.|..|..:..|||.|:.:....:::.:
  Fly   284 HFSTHSKQIRKFRCEPCNMDFITRRGLVAHTKTAPHKRLAKYMQDEFDFIEL 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nom	NP_001262384.1	zf-AD	5..76	CDD:214871	26/77 (34%)
		C2H2 Zn finger	184..204	CDD:275368	5/19 (26%)
		C2H2 Zn finger	212..261	CDD:275368	15/48 (31%)
		zf-H2C2_2	255..278	CDD:290200	10/22 (45%)
		C2H2 Zn finger	269..289	CDD:275368	6/19 (32%)
		zf-H2C2_2	282..305	CDD:290200	7/23 (30%)
		C2H2 Zn finger	297..313	CDD:275368	4/15 (27%)
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	26/79 (33%)
		C2H2 Zn finger	179..199	CDD:275368	5/19 (26%)
		C2H2 Zn finger	211..232	CDD:275368	9/20 (45%)
		C2H2 Zn finger	240..260	CDD:275368	4/19 (21%)
		zf-C2H2_8	243..313	CDD:292531	21/69 (30%)
		C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		C2H2 Zn finger	297..316	CDD:275368	5/18 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.960