DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nom and ZNF784

DIOPT Version :9

Sequence 1:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_976308.1	Gene:	ZNF784 / 147808	HGNCID:	33111	Length:	323	Species:	Homo sapiens

Alignment Length:	175	Identity:	55/175 - (31%)
Similarity:	74/175 - (42%)	Gaps:	44/175 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 KCDTCGIIKNNKSSLVRHQFEHNGIRPYPCKECPKTFLVASELKAHNLTHHTLEP---------- 237
            :|..||......:||..|...|.|.|||.|..||:.|...:.|..|. ..|.:||
Human   102 RCHVCGHSCPGPASLRAHYSLHTGERPYRCALCPRAFKALAPLLRHQ-HRHGVEPGTSRRPPDTA 165

  Fly   238 -----------------------------PFACRYCDRRYFSVVGRKKHERVHTNERPFVCDQCG 273
                                         |||||:|.:.:......:.||||||.|||:.|..||
Human   166 AVAEQRPGVAPERAEVVMAAAAAGAAVGKPFACRFCAKPFRRSSDMRDHERVHTGERPYHCGICG 230

  Fly   274 KAFTRTCILKAHMAVHQVVRKYSCDVCDRSF----SLKKHLATHF 314
            |.||::.:|..|..:|...|.:.|.:|||:|    :.:||..|||
Human   231 KGFTQSSVLSGHARIHTGERPFRCTLCDRTFNNSSNFRKHQRTHF 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nom	NP_001262384.1	zf-AD	5..76	CDD:214871
		C2H2 Zn finger	184..204	CDD:275368	6/19 (32%)
		C2H2 Zn finger	212..261	CDD:275368	18/87 (21%)
		zf-H2C2_2	255..278	CDD:290200	14/22 (64%)
		C2H2 Zn finger	269..289	CDD:275368	8/19 (42%)
		zf-H2C2_2	282..305	CDD:290200	9/26 (35%)
		C2H2 Zn finger	297..313	CDD:275368	7/19 (37%)
ZNF784	NP_976308.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		C2H2 Zn finger	67..87	CDD:275368
		C2H2 Zn finger	103..123	CDD:275368	6/19 (32%)
		C2H2 Zn finger	131..151	CDD:275368	6/20 (30%)
		COG5048	<194..276	CDD:227381	35/82 (43%)
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		C2H2 Zn finger	226..246	CDD:275368	8/19 (42%)
		C2H2 Zn finger	254..274	CDD:275368	7/19 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	269..323		5/7 (71%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	118	1.000	Inparanoid score	I4797
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050