Protein Alignment CG8112 and ARE2

DIOPT Version :10

• Sequence 1: NP_731269.2
• Gene: CG8112 / 41033
• FlyBaseID: FBgn0037612
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_014416.1
• Gene: ARE2 / 855753
• SGDID: S000005302
• Length: 642
• Species: Saccharomyces cerevisiae
• Alignment Length: 566
• Identity: 140/566 - (24%)
• Similarity: 229/566 - (40%)
• Gaps: 129/566 - (22%)

  Fly    39 FEQRLSCMVEDVLQDLR--------QRELRAHEFPNFERSDRKSTWHNRVTSQAPADVSDSTNGH 95
            ||.|.|.:...|.:..:        ::|:|..|   .|....:...|:|.:|....|.....:|.
Yeast   128 FEHRPSILDGSVNEPFKTKFVGPTLEKEIRRRE---KELMAMRKNLHHRKSSPDAVDSVGKNDGA 189

  Fly    96 ANGTHPRPPIQSETSARKQRRQLPEKVFVARESYLTALLQVEHMRTIYHIFYIILVMFLLNVICY 160
            |..|.|       |:|..:.....|...::           .:...:|..|::.:....:..: .
Yeast   190 APTTVP-------TAATSETVVTVETTIIS-----------SNFSGLYVAFWMAIAFGAVKAL-I 235

  Fly   161 DYFVDGRFDLGLGTFRGG------LRRLHWVMGVWLLEHV---FVLALYFAFRGWALVRHKLKPH 216
            ||:....     |:|:..      ...|..|..|.||.::   ||:.:.:..: |.:::
Yeast   236 DYYYQHN-----GSFKDSEILKFMTTNLFTVASVDLLMYLSTYFVVGIQYLCK-WGVLK------ 288

  Fly   217 SSLQRFWSHSCLILYISSQLVFCFVSTSLCLKFN---LPFVSACILLLESTRLLMKMHAFVRYNA 278
                  |..:..|  .:|...|.||...:.|..|   |.::|...|.|.|..||||||:|..||.
Yeast   289 ------WGTTGWI--FTSIYEFLFVIFYMYLTENILKLHWLSKIFLFLHSLVLLMKMHSFAFYNG 345

  Fly   279 ------ERVLNGK---AKKED----------------------AEEEKEGSERPFVPPLSCYTYF 312
                  |.:...|   ||.:|                      :.:......:.|...:|..::|
Yeast   346 YLWGIKEELQFSKSALAKYKDSINDPKVIGALEKSCEFCSFELSSQSLSDQTQKFPNNISAKSFF 410

  Fly   313 LFA--PTLIYRDSYPRTSHIRWKFALNRLLEVVAIAFLYAFIHERHIHEHFGQYGL--------- 366
            .|.  |||||:..||||..|||.:.|.::..:....||..      |......|.:
Yeast   411 WFTMFPTLIYQIEYPRTKEIRWSYVLEKICAIFGTIFLMM------IDAQILMYPVAMRALAVRN 469

  Fly   367 -EPMGPSQLILKLFGMMLPSA----VIFLCGFYLILHSWLNFTSELLRFGDRMFYKDWWTSHTYD 426
             |..|....:||..|:::...    |:::..||||..:.||..:||.|||||.||.|||...::.
Yeast   470 SEWTGILDRLLKWVGLLVDIVPGFIVMYILDFYLIWDAILNCVAELTRFGDRYFYGDWWNCVSWA 534

  Fly   427 GYYRNWNVVVHDWLYEYVYKDMYTHVFRGSKVAASLAVFMISAVVHEQVLGFALQMFFPVM---F 488
            .:.|.||:.||.:|..:||....:. |:.:|..|:|..|.:|:||||    .|:.:.|..:   .
Yeast   535 DFSRIWNIPVHKFLLRHVYHSSMSS-FKLNKSQATLMTFFLSSVVHE----LAMYVIFKKLRFYL 594

  Fly   489 FFFGVVGVALVFL-----MRSAPKVMGNIFLWFSLILGNATLISLY 529
            |||.::.:.||.|     ||:. .::||:..|..:.:|.:.:.:||
Yeast   595 FFFQMLQMPLVALTNTKFMRNR-TIIGNVIFWLGICMGPSVMCTLY 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8112	NP_731269.2	MBOAT	<231..473	CDD:445070	86/291 (30%)
ARE2	NP_014416.1	ARE1	106..642	CDD:227389	140/566 (25%)