Protein Alignment CG8112 and ARE1

DIOPT Version :10

• Sequence 1: NP_731269.2
• Gene: CG8112 / 41033
• FlyBaseID: FBgn0037612
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_009978.1
• Gene: ARE1 / 850415
• SGDID: S000000644
• Length: 610
• Species: Saccharomyces cerevisiae
• Alignment Length: 617
• Identity: 138/617 - (22%)
• Similarity: 233/617 - (37%)
• Gaps: 163/617 - (26%)

  Fly     2 AAERQEKRGEEETQPRLPDLGFVRDKLQKFQSKMLTDFEQRLSCMVEDVLQDLRQRELRAHEFPN 66
            :.|.:...|::|.:...|    |...:||:.|.:
Yeast    65 STEAERVAGKQEQEEEYP----VDAHMQKYLSHL------------------------------- 94

  Fly    67 FERSDRKSTWHNRVTSQAPA---DVSDSTNGHANGTHPRP---------PIQSETSARKQRRQLP 119
              :|..:|.:|.:..|:..:   |||         ..|||         |.|:........:||.
Yeast    95 --KSKSRSRFHRKDASKYVSFFGDVS---------FDPRPTLLDSAINVPFQTTFKGPVLEKQLK 148

  Fly   120 EKVFVARESYLTALLQV--------------EHMRTIYHIFYIILVMFLLNV---ICYDYFVDGR 167
            .......::..|....|              |.:.:.:...|:...|||..:   .|.||:
Yeast   149 NLQLTKTKTKATVKTTVKTTEKTDKADAPPGEKLESNFSGIYVFAWMFLGWIAIRCCTDYY---- 209

  Fly   168 FDLGLGTFRGGLRRLHWVMGVWLLEHVFVLAL----------YFAFRGWALVRHKLKPHSSLQRF 222
                 .::.....:|..|.  ::...:|.:|:          :..|..|.:.:..:.
Yeast   210 -----ASYGSAWNKLEIVQ--YMTTDLFTIAMLDLAMFLCTFFVVFVHWLVKKRIIN-------- 259

  Fly   223 WSHSCLILYISSQLVFCFVSTSLCL-KFNLPFVSACILLLESTRLLMKMHAFVRYNA-----ERV 281
            |..:..:.....:|.|..|:..:.: .|:..:|:...|.|.|...:||.|:|..||.     ::.
Yeast   260 WKWTGFVAVSIFELAFIPVTFPIYVYYFDFNWVTRIFLFLHSVVFVMKSHSFAFYNGYLWDIKQE 324

  Fly   282 LNGKAK-----KEDAEEEK-----------------EGSERPFVPPLSCYTYFLFA--PTLIYRD 322
            |...:|     ||....|.                 :..:..|...:||..:|:|.  |.|:|:.
Yeast   325 LEYSSKQLQKYKESLSPETREILQKSCDFCLFELNYQTKDNDFPNNISCSNFFMFCLFPVLVYQI 389

  Fly   323 SYPRTSHIRWKFALNRLLEVVAIAFLYA-----FIHE---RHIHEH----FGQYGLEPMGPSQLI 375
            :|||||.|||::.|.::..::...||..     |:|.   |.|..|    ||  |..|.......
Yeast   390 NYPRTSRIRWRYVLEKVCAIIGTIFLMMVTAQFFMHPVAMRCIQFHNTPTFG--GWIPATQEWFH 452

  Fly   376 LKLFGMMLPSAVIFLCGFYLILHSWLNFTSELLRFGDRMFYKDWWTSHTYDGYYRNWNVVVHDWL 440
            | ||.|:....|:::..||:|..:.||..:||.||.||.||.|||...:::.:.|.|||.||.:|
Yeast   453 L-LFDMIPGFTVLYMLTFYMIWDALLNCVAELTRFADRYFYGDWWNCVSFEEFSRIWNVPVHKFL 516

  Fly   441 YEYVYKDMYTHVFRG----SKVAASLAVFMISAVVHEQVLGFALQMFFPVMFFF----FGVVGVA 497
            ..:||     |...|    ||..|:|..|.:|||.||..:....:.....:|.|    |....::
Yeast   517 LRHVY-----HSSMGALHLSKSQATLFTFFLSAVFHEMAMFAIFRRVRGYLFMFQLSQFVWTALS 576

  Fly   498 LVFLMRSAPKVMGNIFLWFSLILGNATLISLY 529
            ....:|:.|: :.|:...|.:..|.:.:::||
Yeast   577 NTKFLRARPQ-LSNVVFSFGVCSGPSIIMTLY 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8112	NP_731269.2	MBOAT	<231..473	CDD:445070	87/287 (30%)
ARE1	NP_009978.1	ARE1	96..610	CDD:227389	130/549 (24%)