DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8112 and soat1

DIOPT Version :9

Sequence 1:	NP_731269.2	Gene:	CG8112 / 41033	FlyBaseID:	FBgn0037612	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_001116744.1	Gene:	soat1 / 564424	ZFINID:	ZDB-GENE-081105-177	Length:	554	Species:	Danio rerio

Alignment Length:	571	Identity:	191/571 - (33%)
Similarity:	270/571 - (47%)	Gaps:	60/571 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AERQEKRGEEETQPRLPDLGFVRDKLQKFQSKMLTDFEQRLSCMV------EDVLQDL-RQRELR 60
            |...:|.|.|......|           ..|....:.||.:|..:      |.:..|| ||.:.:
Zfish    19 ASSSDKDGPERDAEEFP-----------LSSNGKVEVEQIISAKLQLKKKAEHLKADLMRQFDAQ 72

  Fly    61 AHEFPNFERSDRKSTWHNRVTSQAPADVSDSTNGHANGTHPRPPIQSETSARKQRRQLPEKVFVA 125
            .:||.:....:..|...:.|::..|  :||..........|              .|...|.||.
Zfish    73 VNEFMDSLIEESASLGSSHVSTVFP--LSDKEKSKLRNAQP--------------SQGQSKQFVI 121

  Fly   126 RESYLTALLQVEHMRTIYHIFYIILVMFLLNVICYDYFVDGR----FDLGLGTFRGGLRRLHWVM 186
            |.|.|..|.:|.|:|||||:|..:|::|:.:.:..|:..:||    |||.:..|    .:...|:
Zfish   122 RRSLLDDLFEVNHIRTIYHMFIALLILFIFSTLVVDFIDEGRLVLEFDLLVYAF----GQFPLVV 182

  Fly   187 GVWLLEHVFVLAL-YFAFRGWALVRHKLKPHSSLQRFWSHSCLILYISSQLVFCFVSTSLCLKFN 250
            ..|:...:..|.: |.....||.: :....|..|....:.|.|::|  ..|...|:.|.:.||..
Zfish   183 VTWMCMFLSTLVVPYVLLVVWAGI-YSSSQHRLLWTVLAGSILLIY--QGLGLGFLPTYVVLKNG 244

  Fly   251 LPFVSACILLLESTRLLMKMHAFVRYNAERVLNGKAKKEDAEEEKEGSERPFVPPLSCYTYFLFA 315
            ||..|..||:||..||:||.|:|:|.|..||         ...::..|....||..:.|.|||||
Zfish   245 LPPASCFILILEQVRLMMKSHSFIRENVPRV---------RSLDRNKSNLVAVPQFTQYIYFLFA 300

  Fly   316 PTLIYRDSYPRTSHIRWKFALNRLLEVVAIAFLYAFIHERHIHEHFGQYGLEPMGPSQLILKLFG 380
            |||||:|:|||...|||.:...:..:|:...|...:|..|.....|....::...|..::|.:|.
Zfish   301 PTLIYKDNYPRNPCIRWGYVATKFSQVLGSLFYAYYIFVRLCIPQFRNISMQLFDPRAMVLCVFN 365

  Fly   381 MMLPSAVIFLCGFYLILHSWLNFTSELLRFGDRMFYKDWWTSHTYDGYYRNWNVVVHDWLYEYVY 445
            .:||..::....|:..||.|||..:|:|||||||||||||.|.:|..|||.||||||||||.|||
Zfish   366 SILPGVLVLFLAFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYANYYRTWNVVVHDWLYYYVY 430

  Fly   446 KDMYTHVFRGSKVAASLAVFMISAVVHEQVLGFALQMFFPVMFFFFGVVGVALVFLM---RSAPK 507
            :|......:..:..|.|.||.:||||||.||......|:||||..|...|:...|::   |..|
Zfish   431 RDFLWMTQKRFRAVAMLVVFTVSAVVHEYVLAICFGFFYPVMFCLFMCFGMVFNFVLHDRRKGP- 494

  Fly   508 VMGNIFLWFSLILGNATLISLYAMEHYALKNCNLSNESWTYRLLPAVWRCY 558
             :.|:.:|.||.||...:|.||:.|.||.:.|.:...|....|.|..|.||
Zfish   495 -IWNVIMWTSLFLGQGVMICLYSQEWYAQRYCPIEEPSLIDLLKPRSWTCY 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8112	NP_731269.2	MBOAT	<231..473	CDD:294479	101/241 (42%)
soat1	NP_001116744.1	MBOAT	255..517	CDD:294479	113/272 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596443
Domainoid	1	1.000	238	1.000	Domainoid score	I2240
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2333
Inparanoid	1	1.050	297	1.000	Inparanoid score	I2709
OMA	1	1.010	-	-		QHG55030
OrthoDB	1	1.010	-	-		D1275897at2759
OrthoFinder	1	1.000	-	-		FOG0003079
OrthoInspector	1	1.000	-	-		otm24696
orthoMCL	1	0.900	-	-		OOG6_105870
Panther	1	1.100	-	-	O	PTHR10408
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2034
SonicParanoid	1	1.000	-	-		X1556
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.940