DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8112 and soat2

DIOPT Version :9

Sequence 1:	NP_731269.2	Gene:	CG8112 / 41033	FlyBaseID:	FBgn0037612	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_001135718.1	Gene:	soat2 / 100216296	XenbaseID:	XB-GENE-961303	Length:	532	Species:	Xenopus tropicalis

Alignment Length:	541	Identity:	177/541 - (32%)
Similarity:	260/541 - (48%)	Gaps:	91/541 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 QRLSCMVEDVLQDLRQRELRAHEFPNFERSDRKSTWHNRVTSQAPADVSDSTNGHANGTHPRPPI 105
            :.:||.::|:|.......:.:::        ||.           |....|...|.|....:..|
Frog    57 EEMSCHLKDLLDKAVAETMHSYK--------RKI-----------ASALSSKKDHVNNKRHQGSI 102

  Fly   106 QSETSARKQRRQLPEKVFVARESYLTALLQVEHMRTIYHIFYIILVMFLLNVICYDYFVDGRFDL 170
            ..:           :|||:.|.|.|..|::|||.|||||:|..:|.:|::|....|....||..|
Frog   103 SEK-----------QKVFMHRASLLDDLMEVEHFRTIYHMFVAVLCVFVINTTAVDIIDQGRLFL 156

  Fly   171 GLGTFRGGLRRLHWVMGVWLLEHVFVLALYFAFRGWAL-VRHKLKPHSSLQRFWSHSCLI-LYIS 233
            .|........:|..|:..||.  :|:..|...:|  || |...|.|.|      ||..|: .:|.
Frog   157 DLDLLFYTFGQLSTVVWTWLC--LFMYTLLVPYR--ALHVLGSLYPES------SHPLLLSAFIG 211

  Fly   234 SQLVFC--FVSTSLCL----KFNLPFVSACILLLESTRLLMKMHAFVRYNAERVLNGKAKKEDAE 292
            ..|:.|  ||...|.:    ::.||..|:.|::||..|.|||.::|:|.....:|  :.:|:|.:
Frog   212 GLLLVCQIFVLGVLPIYVVTQYKLPPASSFIVILEQVRFLMKSYSFLRECVPLLL--RKEKKDIQ 274

  Fly   293 EEKEGSERPFVPPLSCYTYFLFAPTLIYRDSYPRTSHIRWKFALNRLLEVVAIAFLYAFIHERHI 357
                      :|..|.|.||||.||||||:|||||.:|||.|......:.:...|
Frog   275 ----------LPKFSSYLYFLFCPTLIYRESYPRTPYIRWNFVAKNFAQFLGCLF---------- 319

  Fly   358 HEHFGQYGL-------------EPMGPSQLILKLFGMMLPSAVIFLCGFYLILHSWLNFTSELLR 409
               ||.|.|             :|.....|:|.:|...||...:.|..|:..||.|||..:|:||
Frog   320 ---FGYYVLFTLCIPVFTNMSKQPFSNKTLVLSIFHATLPGTFVLLLSFFAFLHCWLNAFAEMLR 381

  Fly   410 FGDRMFYKDWWTSHTYDGYYRNWNVVVHDWLYEYVYKDMYTHVFRGSKVAASLAVFMISAVVHEQ 474
            |.|||||:|||.|.::..|||.||||||||||.|||:|:.:...:..:....|.||::||.|||.
Frog   382 FADRMFYEDWWNSTSFSNYYRTWNVVVHDWLYYYVYRDLLSLCNQRYRAGIMLTVFLLSASVHEY 446

  Fly   475 VLGFALQMFFPVMFFFFGVVGVALVFLM---RSAPKVMGNIFLWFSLILGNATLISLYAMEHYAL 536
            |...:|:.|:||:|..|.:.||...|:|   |.:|  :.|:.:|..|.:|....:.||:.|.||.
Frog   447 VFTLSLRYFYPVLFCLFAIFGVLFNFMMNDKRKSP--VWNVMVWTFLFIGQGIQLCLYSQEWYAQ 509

  Fly   537 KNCNLSNESWTYRLLPAVWRC 557
            .:|.|:.:::...:.|..|.|
Frog   510 IHCPLTEKTFWGLVTPRSWSC 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8112	NP_731269.2	MBOAT	<231..473	CDD:294479	97/260 (37%)
soat2	NP_001135718.1	MBOAT	248..504	CDD:294479	106/282 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	234	1.000	Domainoid score	I2328
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	302	1.000	Inparanoid score	I2628
OMA	1	1.010	-	-		QHG55030
OrthoDB	1	1.010	-	-		D1275897at2759
OrthoFinder	1	1.000	-	-		FOG0003079
OrthoInspector	1	1.000	-	-		otm48177
Panther	1	1.100	-	-	LDO	PTHR10408
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1556
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080