DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hb and Zscan29

DIOPT Version :9

Sequence 1:	NP_731267.1	Gene:	hb / 41032	FlyBaseID:	FBgn0001180	Length:	758	Species:	Drosophila melanogaster
Sequence 2:	NP_001277748.1	Gene:	Zscan29 / 99334	MGIID:	2139317	Length:	834	Species:	Mus musculus

Alignment Length:	173	Identity:	48/173 - (27%)
Similarity:	67/173 - (38%)	Gaps:	34/173 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 EDMKY----MAESEDDDTNIRMPIYNSHGKMKNYKCKTCGVVAITKVDFWAHTRTHM--KPDKIL 269
            ||..|    ..:|...::::|.|:  ||.....|||..||...........|.|.|.  ||.|.|
Mouse   634 EDRPYKYVKYGKSSGSNSHLRYPV--SHEVENPYKCADCGKSFSRSARLIRHQRIHTGEKPYKCL 696

  Fly   270 QCPK-----CPFVTEFKHH--------------------LEYHIRKHKNQKPFQCDKCSYTCVNK 309
            .|.|     ..|:|..:.|                    |..|.|.|..:||:||::|..:..|.
Mouse   697 DCGKGFRDSSNFITHRRIHTGEKPYQCDECGKRFNQSSSLIIHQRTHTGEKPYQCEECGKSFNNS 761

  Fly   310 SMLNSHRKSHSSVYQYRCADCDYATKYCHSFKLHLRKY-GHKP 351
            |..|:||:.|:....:.|.||..:.........|.|.: |.||
Mouse   762 SHFNAHRRIHTGERPHVCPDCGKSFSKSSDLHAHHRTHTGKKP 804

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hb	NP_731267.1	C2H2 Zn finger	242..262	CDD:275368	5/19 (26%)
		C2H2 Zn finger	271..291	CDD:275368	8/44 (18%)
		zf-H2C2_2	283..308	CDD:290200	10/44 (23%)
		C2H2 Zn finger	299..319	CDD:275368	7/19 (37%)
		C2H2 Zn finger	327..345	CDD:275368	4/17 (24%)
		C2H2 Zn finger	707..727	CDD:275371
		C2H2 Zn finger	735..757	CDD:275371
Zscan29	NP_001277748.1	SCAN	13..123	CDD:128708
		SCAN	13..101	CDD:280241
		Myb_DNA-bind_4	238..319	CDD:290549
		Myb_DNA-bind_4	399..480	CDD:290549
		COG5048	<663..823	CDD:227381	40/142 (28%)
		zf-C2H2	665..687	CDD:278523	7/21 (33%)
		C2H2 Zn finger	667..687	CDD:275368	5/19 (26%)
		zf-H2C2_2	680..702	CDD:290200	9/21 (43%)
		C2H2 Zn finger	695..715	CDD:275368	5/19 (26%)
		zf-H2C2_2	707..732	CDD:290200	3/24 (13%)
		C2H2 Zn finger	723..743	CDD:275368	3/19 (16%)
		zf-H2C2_2	735..760	CDD:290200	9/24 (38%)
		C2H2 Zn finger	751..771	CDD:275368	7/19 (37%)
		zf-H2C2_2	763..787	CDD:290200	7/23 (30%)
		zf-C2H2	777..799	CDD:278523	5/21 (24%)
		C2H2 Zn finger	779..799	CDD:275368	5/19 (26%)
		C2H2 Zn finger	807..827	CDD:275368
		zf-C2H2	807..827	CDD:278523
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847309
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930