Protein Alignment hb and ZSCAN5C

DIOPT Version :10

• Sequence 1: NP_731267.1
• Gene: hb / 41032
• FlyBaseID: FBgn0001180
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001345342.1
• Gene: ZSCAN5C / 649137
• HGNCID: 34294
• Length: 496
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 83/373 - (22%)
• Similarity: 131/373 - (35%)
• Gaps: 103/373 - (27%)

  Fly    25 ANIKQEPGHHLDGNSVASSPRQSPIPSTNHLEQFLKQQQQQLQ----------QQPMDTLC---- 75
            |:::.:|.|       .||.|.|   |.|.:.....|..|:||          :|..|.|.
Human   152 ASVRDDPRH-------VSSQRTS---SVNQMCPEEGQASQELQTLPRVPALFRRQEEDFLLPETT 206

  Fly    76 -------AMTPSPSQNDQNSLQHYDANLQQQLLQQQQYQQHFQAAQQQHHHHHHLMGGFNP-LT- 131
                   |:.|.|:             |::.|.:.::.                     || ||
Human   207 VMKGDPKALRPKPT-------------LEKDLEEDREE---------------------NPGLTS 237

  Fly   132 -PPGLPNPMQHFYGGNLRPSPQ--------PTPTSASTIAPVAVATGSSEKLQALTPPMDVTPPK 187
             .|.|||......|......||        ...|.::.:.....:|.|..:..||.  :......
Human   238 PEPQLPNSPTGVVGAKEGKEPQKRASVENVDADTPSACVVEREASTHSGSRGDALN--LRGLKRS 300

  Fly   188 SPAKSSQSNIEPEKEHDQMSNSSEDMKYMAESEDDDTNIRMPIYN-------SHGKMKNYK---- 241
            .|..:|.|..||:.|...:.|....    .::|.:      |:::       ||...:..|
Human   301 KPDATSISQEEPQGEATPVGNRESP----GQAEIN------PVHSPGPAGPVSHPSGQEVKELLP 355

  Fly   242 --CKTCGVVAITKVDFWAHTRTHMKPDKILQCPKCPFVTEFKHHLEYHIRKHKNQKPFQCDKCSY 304
              |:.||.....:.....|||:| ..:::.||..|......:..|::|.|.|..::|:.||.|..
Human   356 FACEVCGKRFKYRGKLAVHTRSH-TGERLFQCNLCGKRFMQRIGLQFHQRTHTGERPYTCDICQK 419

  Fly   305 TCVNKSMLNSHRKSHSSVYQYRCADCDYATKYCHSFKLHLRKY-GHKP 351
            ....||.|..|::||:....:.|.||.....|..:.|.|.|.: |.||
Human   420 QFTQKSYLKCHKRSHTGEKPFECKDCKKVFTYKANLKEHQRIHSGEKP 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hb	NP_731267.1	C2H2 Zn finger	242..262	CDD:275368	6/19 (32%)
		C2H2 Zn finger	271..291	CDD:275368	5/19 (26%)
		zf-H2C2_2	283..308	CDD:463886	8/24 (33%)
		C2H2 Zn finger	299..319	CDD:275368	7/19 (37%)
		C2H2 Zn finger	327..345	CDD:275368	6/17 (35%)
		C2H2 Zn finger	707..727	CDD:275371
		C2H2 Zn finger	735..757	CDD:275371
ZSCAN5C	NP_001345342.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38
		SCAN	40..124	CDD:153421
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..188		13/45 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..347		32/189 (17%)
		zf-C2H2	356..378	CDD:395048	6/21 (29%)
		C2H2 Zn finger	358..378	CDD:275368	6/19 (32%)
		zf-H2C2_2	371..393	CDD:463886	7/22 (32%)
		C2H2 Zn finger	386..406	CDD:275368	5/19 (26%)
		COG5048	410..>473	CDD:227381	20/58 (34%)
		C2H2 Zn finger	414..434	CDD:275368	7/19 (37%)
		C2H2 Zn finger	442..462	CDD:275368	7/19 (37%)
		zf-C2H2	468..490	CDD:395048	83/373 (22%)
		C2H2 Zn finger	470..490	CDD:275368