Protein Alignment hb and OVOL2

DIOPT Version :10

• Sequence 1: NP_731267.1
• Gene: hb / 41032
• FlyBaseID: FBgn0001180
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_067043.2
• Gene: OVOL2 / 58495
• HGNCID: 15804
• Length: 275
• Species: Homo sapiens
• Alignment Length: 182
• Identity: 42/182 - (23%)
• Similarity: 64/182 - (35%)
• Gaps: 29/182 - (15%)

  Fly   190 AKSSQSNIEPEKEHDQMSNSSEDMKYMAESEDDDTNIRMPIYNSHGKMKN--------YKCKTCG 246
            |:||.|...||.|..:..::.....::|..:       .|:..|..|...        :.|..||
Human    68 AESSSSPHAPESETPEPGDAEGPDGHLATKQ-------RPVARSKIKFTTGTCSDSVVHSCDLCG 125

  Fly   247 VVAITKVDFWAHTRTHMKPDKILQCPKCPFVTEFKHHLEYHIRKHKNQKPFQCDKCSYTCVNKSM 311
            .....:.....|.:.|.:..:.| |..|.........|:.|:|.|...:|::|:.|:.....:..
Human   126 KGFRLQRMLNRHLKCHNQVKRHL-CTFCGKGFNDTFDLKRHVRTHTGIRPYKCNVCNKAFTQRCS 189

  Fly   312 LNSHRKSHSSVYQ-----------YRCADCDYATKYCHSFKLHLRKYGHKPG 352
            |.||.|....|.|           |.|.||.|.........||:.. .| ||
Human   190 LESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNS-AH-PG 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hb	NP_731267.1	C2H2 Zn finger	242..262	CDD:275368	4/19 (21%)
		C2H2 Zn finger	271..291	CDD:275368	5/19 (26%)
		zf-H2C2_2	283..308	CDD:463886	7/24 (29%)
		C2H2 Zn finger	299..319	CDD:275368	6/19 (32%)
		C2H2 Zn finger	327..345	CDD:275368	6/17 (35%)
		C2H2 Zn finger	707..727	CDD:275371
		C2H2 Zn finger	735..757	CDD:275371
OVOL2	NP_067043.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..101		8/39 (21%)
		C2H2 Zn finger	121..141	CDD:275368	4/19 (21%)
		C2H2 Zn finger	149..169	CDD:275368	5/19 (26%)
		zf-H2C2_2	161..186	CDD:463886	7/24 (29%)
		C2H2 Zn finger	177..198	CDD:275368	6/20 (30%)
		C2H2 Zn finger	216..233	CDD:275368	5/16 (31%)