DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hb and SCAND1

DIOPT Version :9

Sequence 1:	NP_731267.1	Gene:	hb / 41032	FlyBaseID:	FBgn0001180	Length:	758	Species:	Drosophila melanogaster
Sequence 2:	NP_001372639.1	Gene:	SCAND1 / 51282	HGNCID:	10566	Length:	179	Species:	Homo sapiens

Alignment Length:	95	Identity:	28/95 - (29%)
Similarity:	39/95 - (41%)	Gaps:	18/95 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   381 GGPIA-------SGGSGSGSRKSNVAAVAPQQQQSQPAQPVATSQLSAALQGFPLVQGNSAPPAA 438
            |.|.|       ..||.|...::.|.:..|   ::.|..|..:|..:|..:..|..:.     ||
Human    12 GSPAAVPPEKLEGAGSSSAPERNCVGSSLP---EASPPAPEPSSPNAAVPEAIPTPRA-----AA 68

  Fly   439 SPVLPLPASPAK-SVA--SVEQTPSLPSPA 465
            |..|.||..||. |||  :..:..|.|.||
Human    69 SAALELPLGPAPVSVAPQAEAEARSTPGPA 98

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hb	NP_731267.1	C2H2 Zn finger	242..262	CDD:275368
		C2H2 Zn finger	271..291	CDD:275368
		zf-H2C2_2	283..308	CDD:290200
		C2H2 Zn finger	299..319	CDD:275368
		C2H2 Zn finger	327..345	CDD:275368
		C2H2 Zn finger	707..727	CDD:275371
		C2H2 Zn finger	735..757	CDD:275371
SCAND1	NP_001372639.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..104		28/95 (29%)
SCAND1	NP_001372639.1	SCAN	104..>162	CDD:396558
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156885
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930