DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hb and CG7691

DIOPT Version :9

Sequence 1:	NP_731267.1	Gene:	hb / 41032	FlyBaseID:	FBgn0001180	Length:	758	Species:	Drosophila melanogaster
Sequence 2:	NP_650728.1	Gene:	CG7691 / 42228	FlyBaseID:	FBgn0038626	Length:	283	Species:	Drosophila melanogaster

Alignment Length:	279	Identity:	58/279 - (20%)
Similarity:	86/279 - (30%)	Gaps:	114/279 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 NLRPSPQPTPTSASTIA------------------------------PVAVATGSSEKL--QALT 178
            ||.|.|:|.....|.:|                              |:.|.....|:|  |.:
  Fly    33 NLPPMPRPKTNHHSRVATKPEPKTNVKFTYCFGQSEPSGDWRQGDDIPIVVRREMEERLGIQLM- 96

  Fly   179 PPMDVTPPKSPAKSSQSNIEPEKEHDQMSNSSEDMKYMAESEDDDTNIRMPIYNSHGKMKNYKCK 243
                             ::.|..|...:|::..::|...||.|.....|..|
  Fly    97 -----------------SVLPITESSLLSHTIWELKMPGESFDSIPKTRNGI------------- 131

  Fly   244 TCGVVAITKVDFWAHTRTHMK-----------PDKILQCP-----KCP----------------F 276
            ..|::.:|...  ..|||.:|           |..|::.|     |.|                .
  Fly   132 KVGIITVTAES--KQTRTKLKRKGPILANVTVPSNIVEIPPIQQRKMPEKRRLKRVGGQFECIDC 194

  Fly   277 VTEFKHH--LEYHIRKHKNQKPFQC--DKCSYTCVNKSMLNSHRKS--HSSVYQYRCADCDYATK 335
            ..:|.|.  |..|.|.|..:|||.|  ..|.....::|.|.||:::  |.. :|::|..|.   |
  Fly   195 DKKFDHSWMLTAHTRTHTGEKPFVCPDGSCRKAFSDRSNLRSHQRTMGHHE-WQHQCGQCG---K 255

  Fly   336 YCHSFKL---H----LRKY 347
            |...|..   |    .|||
  Fly   256 YFSQFSYLNRHSLDACRKY 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hb	NP_731267.1	C2H2 Zn finger	242..262	CDD:275368	4/19 (21%)
		C2H2 Zn finger	271..291	CDD:275368	8/42 (19%)
		zf-H2C2_2	283..308	CDD:290200	9/28 (32%)
		C2H2 Zn finger	299..319	CDD:275368	6/23 (26%)
		C2H2 Zn finger	327..345	CDD:275368	6/24 (25%)
		C2H2 Zn finger	707..727	CDD:275371
		C2H2 Zn finger	735..757	CDD:275371
CG7691	NP_650728.1	COG5048	188..>271	CDD:227381	23/86 (27%)
		C2H2 Zn finger	191..211	CDD:275368	5/19 (26%)
		zf-H2C2_2	203..229	CDD:290200	9/25 (36%)
		C2H2 Zn finger	219..244	CDD:275368	6/24 (25%)
		C2H2 Zn finger	250..266	CDD:275368	5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100