DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hb and Scand1

DIOPT Version :9

Sequence 1:	NP_731267.1	Gene:	hb / 41032	FlyBaseID:	FBgn0001180	Length:	758	Species:	Drosophila melanogaster
Sequence 2:	NP_001102069.1	Gene:	Scand1 / 362252	RGDID:	1308530	Length:	142	Species:	Rattus norvegicus

Alignment Length:	136	Identity:	32/136 - (23%)
Similarity:	50/136 - (36%)	Gaps:	26/136 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   398 VAAVAPQQQQSQPAQPVATSQLSAALQGFPLVQGNSAPPAASPVLPLPASPAKSVASVEQTPSLP 462
            :||..|.|....||.|....      :|............:||...||.:|| ::.:..|..:.|
  Rat     1 MAAPQPSQAAQSPAAPPEQE------EGAGDCAAREPDSMSSPAPELPGAPA-ALNTAPQADAAP 58

  Fly   463 SPANLLPPLASLLQQNRNMAFFPYWNLNLQMLAAQQQA-AVLAQLSP-------RMREQLQQ--- 516
            .|....|...:..|:.|...:        |..|..::| ..|.:||.       |.:||:.:
  Rat    59 RPGASRPGPETFRQRFRQFRY--------QDAAGPREAFRQLRELSRQWLRPDIRTKEQIVEMLV 115

  Fly   517 QNQQQS 522
            |.|.|:
  Rat   116 QEQLQA 121

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hb	NP_731267.1	C2H2 Zn finger	242..262	CDD:275368
		C2H2 Zn finger	271..291	CDD:275368
		zf-H2C2_2	283..308	CDD:290200
		C2H2 Zn finger	299..319	CDD:275368
		C2H2 Zn finger	327..345	CDD:275368
		C2H2 Zn finger	707..727	CDD:275371
		C2H2 Zn finger	735..757	CDD:275371
Scand1	NP_001102069.1	SCAN	67..>125	CDD:280241	14/63 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350840
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930