DRSC/TRiP Functional Genomics Resources

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Protein Alignment hb and Plagl2

DIOPT Version :9

Sequence 1:NP_731267.1 Gene:hb / 41032 FlyBaseID:FBgn0001180 Length:758 Species:Drosophila melanogaster
Sequence 2:XP_006235347.1 Gene:Plagl2 / 296281 RGDID:1307999 Length:496 Species:Rattus norvegicus


Alignment Length:379 Identity:80/379 - (21%)
Similarity:122/379 - (32%) Gaps:136/379 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   234 HGKMKNYKCKT--CGVVAITKVDFWAHTRTH--MKPDKILQCPKCPFVTEFKHHLEYHIRKH-KN 293
            |.:.:.|.|..  ||....:|...:.|..||  .||.   ||..|..:...|.||..|::.| .|
  Rat    62 HPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPH---QCMYCDKMFHRKDHLRNHLQTHDPN 123

  Fly   294 QKPFQCDKCS-----------------------------YTCVNKSMLNSHRKSHS-------SV 322
            ::...|.:|.                             .|..:...|..|.|:||       ..
  Rat   124 KEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSRRVAGGAKE 188

  Fly   323 YQYRCADC---------------------DYATKYC------------HSFKLH---LRKYGHKP 351
            .::.|..|                     |:..:||            |..|.|   |.|...:|
  Rat   189 KKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEP 253

  Fly   352 ----GMV-------LDEDGTPNPSLVI-DVYGTRRGPKSKNGGPIASGGSG--------SGSRKS 396
                |::       :.|:.:|...:.. |:.|.:..|     |.:..|..|        :|...|
  Rat   254 VDMLGLLSCSSTVSVKEELSPVLCMASRDMMGAKAFP-----GMLPMGMYGAHIPTMPSAGMPHS 313

  Fly   397 NVAAVAPQQQQSQPAQPVATSQLSAALQGFPLVQGNSAP------------------PAA---SP 440
            .|....|...    :.|:.:|.:|::.|..|..|..|..                  |.:   |.
  Rat   314 LVHNTLPMGM----SYPLESSPISSSAQLPPKYQLGSTSYLPDKLPKVEVDSFLAELPGSLSLSS 374

  Fly   441 VLPLPAS--PAKSVASVEQTPSLPSPANLLPPL-ASLLQQNRNMAFFPYWNLNL 491
            ..|.|||  ||.:.|.:::.....|||||...| |:.:..:..:.|.|   |||
  Rat   375 AEPQPASPQPAAAAALLDEALLTKSPANLSEALCAANVDFSHLLGFLP---LNL 425

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hbNP_731267.1 C2H2 Zn finger 242..262 CDD:275368 5/21 (24%)
C2H2 Zn finger 271..291 CDD:275368 6/19 (32%)
zf-H2C2_2 283..308 CDD:290200 8/54 (15%)
C2H2 Zn finger 299..319 CDD:275368 6/48 (13%)
C2H2 Zn finger 327..345 CDD:275368 8/53 (15%)
C2H2 Zn finger 707..727 CDD:275371
C2H2 Zn finger 735..757 CDD:275371
Plagl2XP_006235347.1 C2H2 Zn finger 42..62 CDD:275368 80/379 (21%)
C2H2 Zn finger 70..92 CDD:275368 5/21 (24%)
zf-H2C2_2 85..109 CDD:290200 8/26 (31%)
C2H2 Zn finger 100..120 CDD:275368 6/19 (32%)
C2H2 Zn finger 129..149 CDD:275368 2/19 (11%)
C2H2 Zn finger 158..178 CDD:275368 4/19 (21%)
C2H2 Zn finger 193..213 CDD:275368 2/19 (11%)
C2H2 Zn finger 221..239 CDD:275368 3/17 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166350838
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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