DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hb and Ovol2

DIOPT Version :9

Sequence 1:	NP_731267.1	Gene:	hb / 41032	FlyBaseID:	FBgn0001180	Length:	758	Species:	Drosophila melanogaster
Sequence 2:	XP_038960525.1	Gene:	Ovol2 / 296201	RGDID:	1306130	Length:	274	Species:	Rattus norvegicus

Alignment Length:	182	Identity:	42/182 - (23%)
Similarity:	65/182 - (35%)	Gaps:	29/182 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 AKSSQSNIEPEKEHDQMSNSSEDMKYMAESEDDDTNIRMPIYNSHGKMKN--------YKCKTCG 246
            |:||.|...||.|..::.::.....::|.       ::.|:..|..|...        :.|..||
  Rat    67 AESSSSPRAPEPETPELHDAEGTDGHLAA-------MQRPVARSKIKFTTGTCNDSVIHNCDLCG 124

  Fly   247 VVAITKVDFWAHTRTHMKPDKILQCPKCPFVTEFKHHLEYHIRKHKNQKPFQCDKCSYTCVNKSM 311
            .....:.....|.:.|.:..:.| |..|.........|:.|:|.|...:|::|:.|......:..
  Rat   125 KSFRLQRMLNRHLKCHNQVKRHL-CTFCGKGFNDTFDLKRHVRTHTGIRPYKCEVCYKAFTQRCS 188

  Fly   312 LNSHRKSHSSVYQ-----------YRCADCDYATKYCHSFKLHLRKYGHKPG 352
            |.||.|....|.|           |.|.||.|.........||:.. .| ||
  Rat   189 LESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNS-AH-PG 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hb	NP_731267.1	C2H2 Zn finger	242..262	CDD:275368	4/19 (21%)
		C2H2 Zn finger	271..291	CDD:275368	5/19 (26%)
		zf-H2C2_2	283..308	CDD:290200	7/24 (29%)
		C2H2 Zn finger	299..319	CDD:275368	6/19 (32%)
		C2H2 Zn finger	327..345	CDD:275368	6/17 (35%)
		C2H2 Zn finger	707..727	CDD:275371
		C2H2 Zn finger	735..757	CDD:275371
Ovol2	XP_038960525.1	COG5048	118..>169	CDD:227381	11/51 (22%)
		C2H2 Zn finger	120..140	CDD:275368	4/19 (21%)
		C2H2 Zn finger	148..168	CDD:275368	5/19 (26%)
		zf-H2C2_2	160..185	CDD:404364	7/24 (29%)
		zf-C2H2_3rep	176..>237	CDD:408638	16/62 (26%)
		C2H2 Zn finger	176..197	CDD:275368	6/20 (30%)
		C2H2 Zn finger	215..232	CDD:275368	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350862
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930