DRSC/TRiP Functional Genomics Resources

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Protein Alignment hb and Zfp770

DIOPT Version :9

Sequence 1:NP_731267.1 Gene:hb / 41032 FlyBaseID:FBgn0001180 Length:758 Species:Drosophila melanogaster
Sequence 2:NP_780675.1 Gene:Zfp770 / 228491 MGIID:2445100 Length:705 Species:Mus musculus


Alignment Length:579 Identity:104/579 - (17%)
Similarity:175/579 - (30%) Gaps:188/579 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   196 NIEPEKEHDQMSNSSEDMKYMAESEDDDTNIRMPIYNSHGKMKNYKCKTCGVVAITKVDFWA-HT 259
            |::...:|.|:.|         ||..:|..:|..:.....|.....|.|     .|..:.|| |.
Mouse    96 NLKTFVKHQQLHN---------ESYHNDVKVRRLLETKQEKPVYGMCNT-----FTADERWALHP 146

  Fly   260 --------RTHMKPDKILQCPKCPFVTEFKHHLEYHIRKHKNQKPFQCDKCSYTCVNKSMLNSHR 316
                    .|..:...|..|..|..:...:..|:.|...|..|:||:|..||.:....:.|..|:
Mouse   147 CSKSDATYSTTKRRKNIHACTICGKMFPSQSKLDRHSLIHTGQRPFKCVLCSKSFRQSTHLKIHQ 211

  Fly   317 KSHSSVYQYRCADCDYATKYCHSFKLHLRKYGHK------------PGMVLDEDGTPNPSLVIDV 369
            .:||....::|..|.      ..||:..:...||            |..|...:..|.|:.:   
Mouse   212 LTHSEERPFQCCFCQ------KGFKIQSKLLKHKQIHTRNKTLQNLPLKVKSPESCPLPNKL--- 267

  Fly   370 YGTRRGPKSKNGGPIASGGSGSGSRKSNVAAVAPQQQQSQPAQPVATSQLSAALQGFPLVQGNSA 434
                    :.......||..|. |.::|     |....|....|...|:.....:...::.|:..
Mouse   268 --------NAKQDAFESGDMGE-SEENN-----PLDVHSIYIVPFQCSECEECFESEQILNGHKC 318

  Fly   435 PPAASPVLPLPASPAKSVASVEQTPSLPSPANLLPPLASLLQQNRNMAFFPYWNLNLQMLAAQQQ 499
            .||....:|                             |.|:::.|     |..:..::||    
Mouse   319 LPARGGRVP-----------------------------SRLKRSCN-----YKTIVKKLLA---- 345

  Fly   500 AAVLAQLSPRMREQLQQQNQQQSDNEEEEQDDEYERKSVDSAMDLSQGTPVKEDEQQQQPQQPLA 564
                         :|::...::||:.:.|:...::...:.:. :.|.|.|     ..:|.|:...
Mouse   346 -------------KLKRAGGKKSDDLQSEKKRTFKSNYLKNC-ERSSGKP-----NIEQTQRTFV 391

  Fly   565 MNLKVEEEATPLMSSSNASRRKGRVLKLDTLLQLRSEAMTSPEQLKVPSTPMPTASSPIAGRKPM 629
            .:|....      |....|::|.:.|.|                             |.:.:|..
Mouse   392 GSLSRHG------SYKTVSKKKKKTLAL-----------------------------PFSWQKQF 421

  Fly   630 PEEHCSGTSSADESMETAHVPQANTSASSTASSSGNSSNASSNSNGNSS-------------SNS 681
                        :|..|....|...:..|..|..|:.:|...:..|:|.             |:|
Mouse   422 ------------QSQNTGKSLQGILTTGSILSMDGSVNNKDLSIYGSSGEEYLNCDMLQCGFSDS 474

  Fly   682 SSNGTTSAVAAPPSGTPAAAGAIYECKYCDIFFKDAVLYTIHMGYHSCDDVFKCNMCGE 740
            |.|..|.....|             |..||..|........|...|:....|.||:||:
Mouse   475 SENIHTGHKMCP-------------CDKCDKVFPSISKLQRHYLIHTGQRPFDCNVCGK 520

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hbNP_731267.1 C2H2 Zn finger 242..262 CDD:275368 6/28 (21%)
C2H2 Zn finger 271..291 CDD:275368 4/19 (21%)
zf-H2C2_2 283..308 CDD:290200 9/24 (38%)
C2H2 Zn finger 299..319 CDD:275368 5/19 (26%)
C2H2 Zn finger 327..345 CDD:275368 4/17 (24%)
C2H2 Zn finger 707..727 CDD:275371 5/19 (26%)
C2H2 Zn finger 735..757 CDD:275371 4/6 (67%)
Zfp770NP_780675.1 C2H2 Zn finger 33..53 CDD:275368
zf-H2C2_2 46..70 CDD:404364
C2H2 Zn finger 61..81 CDD:275368
C2H2 Zn finger 87..107 CDD:275368 3/10 (30%)
C2H2 Zn finger 166..186 CDD:275368 4/19 (21%)
zf-H2C2_2 179..203 CDD:404364 9/23 (39%)
C2H2 Zn finger 194..214 CDD:275368 5/19 (26%)
C2H2 Zn finger 222..242 CDD:275368 6/25 (24%)
C2H2 Zn finger 487..507 CDD:275368 5/19 (26%)
zf-H2C2_2 500..524 CDD:404364 7/21 (33%)
C2H2 Zn finger 515..535 CDD:275368 4/6 (67%)
C2H2 Zn finger 642..662 CDD:275368
zf-H2C2_2 655..679 CDD:404364
C2H2 Zn finger 670..690 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167847287
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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