Protein Alignment hb and Peg3

DIOPT Version :10

• Sequence 1: NP_731267.1
• Gene: hb / 41032
• FlyBaseID: FBgn0001180
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_017444130.1
• Gene: Peg3 / 103691034
• RGDID: 2323590
• Length: 1660
• Species: Rattus norvegicus
• Alignment Length: 655
• Identity: 128/655 - (19%)
• Similarity: 208/655 - (31%)
• Gaps: 182/655 - (27%)

  Fly   180 PMDVTP-PKSPAKSSQSNIEPEKEH--DQMSNSSE---DMKYMAESEDDDTNIRMPI-------- 230
            |.|..| .|.|......:.||:.:.  ||...|.|   |..:..|...|:.:.:.|:
  Rat  1081 PQDKEPQDKEPQDKQPQDKEPQDKEPLDQEMRSEEPHGDQPHGQEPHGDEPHDKEPVDQEMPSEE 1145

  Fly   231 ---YNSHGKMKN----------------------YKCKTCGVVAITKVDFWAHTRTHMKPDKILQ 270
               ..|||:.|.                      |:|:.||:......|..:|...|.:...:..
  Rat  1146 PQGEESHGQEKAEDITIETSVSEEPQKDDAGDAIYECQDCGLGFADLNDLTSHQDVHSRKSLVDS 1210

  Fly   271 CPKCPFVTEFKHHLEYHI-------RKHKNQKPFQCDKCSYTCVNKSMLNSHRKSHSSVYQYRCA 328
                   .|:.|. |.|:       :|:..:|.::|.||..:.::.|:|..|::.|..
  Rat  1211 -------REYTHS-EVHVHSVSEFEKKYSGEKLYECPKCGESFIHSSLLFEHQRVHEQ------- 1260

  Fly   329 DCDYATKYCHSFKLHLRKYGHKPGMVLDEDGTPNPSLVIDVYGTRRGPKSKNGGPIASGGSGSGS 393
            |..|:.|.|..            |.:......|..:..::     |.| :.:|..|.....|.|.
  Rat  1261 DQTYSVKACDD------------GFIALLPARPRRNCTVE-----RNP-AVSGSAIRCRQCGQGF 1307

  Fly   394 RKSNVAAVAPQQQQSQPAQPVATSQLS--AALQGFPLV--QGNSAPPAASPVL------------ 442
            ..|  :|:....:|.:..:.:..::|:  ..:||..|.  ||:..........
  Rat  1308 IHS--SALNEHMRQHRDNEILEQNELADEIFIQGLALTEYQGSETEEKLFECTICGECFFTAKQL 1370

  Fly   443 -----------PLPASPAKSVASVEQTPSLPSPANLLPPL-------ASLLQQ---NRNMAFFPY 486
                       |....|:.:.||.     |..|.....||       .|.|..   ...|.|.|.
  Rat  1371 GDHHTKVHKDEPYEYGPSYTHASF-----LTEPLRKHIPLYECKDCGQSFLDDTVITERMVFHPE 1430

  Fly   487 WNLNLQMLAAQQQAAVLAQLSPRMREQLQQQNQQQSDNEEEEQDDEYE--RKSVDSA-----MDL 544
            .....:::||..|......|.|:...::|..|.:.::.|.|..:.|.|  ...|::|     .:.
  Rat  1431 REGGSEIVAATAQEVEANVLIPQEVLRIQGSNAEAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEG 1495

  Fly   545 SQGTPVKEDEQQQQP----QQPLAMNLKVEEEATPLMSSSNASRRKGRVLKLDTLLQLRSEAMTS 605
            ..|...:.|.:.:||    :||                :.:|....|..:: |.     .|....
  Rat  1496 PDGEAAEPDGEAEQPNGEAEQP----------------NGDADEPDGAGIE-DP-----EERADE 1538

  Fly   606 PEQLKVPSTPMPTASSPIAGRKPMPEEHCSGTSSADESMETAHVPQ------ANTSASSTASSSG 664
            ||:  ....|...|..|.......|||     ...|:.:|... |.      |.|.|||.|....
  Rat  1539 PEE--DVEEPEGDADEPDGADIEDPEE-----EGEDQEIEVEE-PYYNCHECAETFASSAAFGEH 1595

  Fly   665 NSSNAS------SNSNGNSSSNSSSNGTTSAVAAPPSGTPAAAGAIYECKYCDIFFKDAVLYTIH 723
            ..|:||      :|:.|..|      |.....:....|...|....::|..|...|.|.:....|
  Rat  1596 LKSHASVIIFEPANALGECS------GYIERASTSAGGAEQADDKYFKCDVCGQLFNDRLSLARH 1654

  Fly   724 MGYHS 728
            ...|:
  Rat  1655 QNSHT 1659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hb	NP_731267.1	C2H2 Zn finger	242..262	CDD:275368	5/19 (26%)
		C2H2 Zn finger	271..291	CDD:275368	4/26 (15%)
		zf-H2C2_2	283..308	CDD:463886	7/31 (23%)
		C2H2 Zn finger	299..319	CDD:275368	6/19 (32%)
		C2H2 Zn finger	327..345	CDD:275368	4/17 (24%)
		C2H2 Zn finger	707..727	CDD:275371	5/19 (26%)
		C2H2 Zn finger	735..757	CDD:275371
Peg3	XP_017444130.1	C2H2 Zn finger	408..428	CDD:275368
		zf-C2H2	459..481	CDD:395048
		C2H2 Zn finger	461..481	CDD:275368
		C2H2 Zn finger	519..539	CDD:275368
		C2H2 Zn finger	607..627	CDD:275368
		C2H2 Zn finger	637..656	CDD:275368
		zf-C2H2	934..956	CDD:395048
		C2H2 Zn finger	936..956	CDD:275368
		PHA03169	946..>1176	CDD:223003	19/94 (20%)
		C2H2 Zn finger	1182..1202	CDD:275368	5/19 (26%)
		zf-C2H2	1236..1258	CDD:395048	6/21 (29%)
		C2H2 Zn finger	1238..1258	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1300..1320	CDD:275368	4/21 (19%)
		C2H2 Zn finger	1357..1378	CDD:275368	0/20 (0%)
		C2H2 Zn finger	1579..1599	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1638..1658	CDD:275368	5/19 (26%)