Protein Alignment CG8043 and IBA57

DIOPT Version :10

• Sequence 1: NP_649814.1
• Gene: CG8043 / 41030
• FlyBaseID: FBgn0037610
• Length: 348
• Species: Drosophila melanogaster
• Sequence 2: NP_001010867.1
• Gene: IBA57 / 200205
• HGNCID: 27302
• Length: 356
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 122/373 - (32%)
• Similarity: 162/373 - (43%)
• Gaps: 86/373 - (23%)

  Fly     8 WFLRAVRHHIRNLHEMRIPYARP-VGPNQRNFTLEPLGNRELIRVHGAEVVPFLQGLATNDVARI 71
            |.|||. ...|..|....|...| .|.....|.|:   .|.|:||.|.:..|||.||.||::. :
Human    21 WRLRAA-PRCRLAHSSCSPGGDPTAGAAWACFRLD---GRTLLRVRGPDAAPFLLGLLTNELP-L 80

  Fly    72 QSP---GGPASM---YAHFLNKAGRLLYDTILYRTNNPETI---LVECDREASSDFRRHLRTYRV 127
            .||   |.|.:.   ||||||..||.|||.|||.......:   |:|||.......::||..||:
Human    81 PSPAAAGAPPAARAGYAHFLNVQGRTLYDVILYGLQEHSEVSGFLLECDSSVQGALQKHLALYRI 145

  Fly   128 RRRIEVDSVDDEYTPWVMFNLKDASEAVPNPHPDLFV------SP-------------------- 166
            ||::.|:                       |||:|.|      ||
Human   146 RRKVTVE-----------------------PHPELRVWAVLPSSPEACGAASLQERAGAAAILIR 187

  Fly   167 DPRLHVLGTRIL----APTDMDWSKLSKCFADFGTATAASSDNSYQLLRYKQGVGEGCSELTPGK 227
            |||...:|.|:|    .|..:...:|...:             .|...||.|||.||..:|.||.
Human   188 DPRTARMGWRLLTQDEGPALVPGGRLGDLW-------------DYHQHRYLQGVPEGVRDLPPGV 239

  Fly   228 CFPLEANADYLHGVSFHKGCYVGQELTARVHHSGVIRKRYMPIRLTAPI---DVGSSQDVTSLAG 289
            ..|||:|..:::||||.||||:|||||||.||.||||||..|:|...|:   .:.....|.:.:|
Human   240 ALPLESNLAFMNGVSFTKGCYIGQELTARTHHMGVIRKRLFPVRFLDPLPTSGITPGATVLTASG 304

  Fly   290 AKLGRVFGFAHKHGIALLRIEKVLNGRPELMIDGERCYVER--PEWWP 335
            ..:|:........|:|||..||:.........:|.:..:..  |:|||
Human   305 QTVGKFRAGQGNVGLALLWSEKIKGPLHIRASEGAQVALAASVPDWWP 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8043	NP_649814.1	YgfZ	23..310	CDD:440123	109/329 (33%)
IBA57	NP_001010867.1	YgfZ	49..344	CDD:440123	109/334 (33%)