DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL19 and MRPL19

DIOPT Version :9

Sequence 1:	NP_524284.1	Gene:	mRpL19 / 41028	FlyBaseID:	FBgn0037608	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_055578.2	Gene:	MRPL19 / 9801	HGNCID:	14052	Length:	292	Species:	Homo sapiens

Alignment Length:	249	Identity:	116/249 - (46%)
Similarity:	165/249 - (66%)	Gaps:	23/249 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 PPTTPTSPVNRKTIIPANYRFVYPEFLP-----DPKVEWRNLVREKLERLDMLDRRKQIDLPEFY 103
            ||..|......:.:.|.. ||:.|||:|     ||       ::.::||.|||:|||.:.:||||
Human    56 PPPKPVIVDKHRPVEPER-RFLSPEFIPRRGRTDP-------LKFQIERKDMLERRKVLHIPEFY 112

  Fly   104 VGSVLAVTSSDPHAAGKTSRFVGICINRDRCGLRARFILRNVIDHQGMEVVYELYDPTILKIEVL 168
            |||:|.||::||:|:||.|:|:||||.|...||.|.|||||||:.||:|:.:|||:|.:.:|:|:
Human   113 VGSILRVTTADPYASGKISQFLGICIQRSGRGLGATFILRNVIEGQGVEICFELYNPRVQEIQVV 177

  Fly   169 RLEKRLDDSLFYLRDALPEYSTFDENMEAEPLEEGAPVPVNDIKVVLRPRPWLERWERQ--NLRG 231
            :|||||||||.|||||||||||||.||:....|....||||::||.::|:||.:||||.  |::|
Human   178 KLEKRLDDSLLYLRDALPEYSTFDVNMKPVVQEPNQKVPVNELKVKMKPKPWSKRWERPNFNIKG 242

  Fly   232 VANIDEYLKDKHRLSAAKVQKPWEKYDMMKDYRSSIPEEEQTEIFAEVHTELHA 285
            : ..|..|.::....|.|..:||.::|||::|.:|       :|.|.:..|:.|
Human   243 I-RFDLCLTEQQMKEAQKWNQPWLEFDMMREYDTS-------KIEAAIWKEIEA 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL19	NP_524284.1	Ribosomal_L19	94..183	CDD:294284	54/88 (61%)
MRPL19	NP_055578.2	Ribosomal_L19	108..192	CDD:412361	52/83 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157086
Domainoid	1	1.000	119	1.000	Domainoid score	I5829
eggNOG	1	0.900	-	-		E1_COG0335
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8851
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3608
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1387536at2759
OrthoFinder	1	1.000	-	-		FOG0004273
OrthoInspector	1	1.000	-	-		oto90490
orthoMCL	1	0.900	-	-		OOG6_101282
Panther	1	1.100	-	-	LDO	PTHR15680
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2755
SonicParanoid	1	1.000	-	-		X5327
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.790