DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL19 and mrpl-19

DIOPT Version :9

Sequence 1:	NP_524284.1	Gene:	mRpL19 / 41028	FlyBaseID:	FBgn0037608	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_491381.1	Gene:	mrpl-19 / 172052	WormBaseID:	WBGene00022470	Length:	288	Species:	Caenorhabditis elegans

Alignment Length:	267	Identity:	126/267 - (47%)
Similarity:	170/267 - (63%)	Gaps:	17/267 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 QEEQKKEAPPTTPTSPVNRKTIIPANYRFVYPEFLPDPKVEWRNLVREKLERLDMLDRRKQIDLP 100
            :.|..:.||.|..||......:||| :..:||:||..|....||.::|:|||.|||:||..||:|
Worm    20 KSEPTRAAPVTKKTSREEIAGLIPA-FPEIYPDFLQSPVWNRRNALKEELERQDMLERRMNIDIP 83

  Fly   101 EFYVGSVLAVTSSDPHAAGKTSRFVGICINRDRCGLRARFILRNVIDHQGMEVVYELYDPTILKI 165
            ||||||::||||||.:...|..|||||||.|::.||..:|.|||.|::.|:||||:||:|||.||
Worm    84 EFYVGSIVAVTSSDKNLGSKEHRFVGICIRREKEGLLHQFTLRNTIENIGVEVVYDLYNPTIKKI 148

  Fly   166 EVLRLEKRLDDSLFYLRDALPEYSTFDENMEAEPLEEGAPVPVNDIKVVLRPRPWLERWERQNLR 230
            |.|:||||||:.|.||.||||||||||.:||.:....|.|:|||:.||.|:..||..|||..::|
Worm   149 ETLKLEKRLDNDLSYLVDALPEYSTFDFHMEPQAHPAGTPIPVNECKVKLKTPPWTRRWEVASVR 213

  Fly   231 GV----ANIDEYLKDK-HRLSAAKVQKPWEKYDMMKDYRSSIPEEEQTEIFAE-----VHTELHA 285
            |:    .....:.|.| |:    .:...:||||::.|||:|..:|:  |:|.:     ...|.||
Worm   214 GIEDTWTQATPWFKRKLHK----TIVNDYEKYDLIADYRTSSTKEQ--EVFVQKQMQKFEKERHA 272

  Fly   286 LELQRKR 292
            ..|.|:|
Worm   273 AGLTRRR 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL19	NP_524284.1	Ribosomal_L19	94..183	CDD:294284	55/88 (63%)
mrpl-19	NP_491381.1	Ribosomal_L19	75..>155	CDD:294284	48/79 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165280
Domainoid	1	1.000	112	1.000	Domainoid score	I3901
eggNOG	1	0.900	-	-		E1_COG0335
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8851
Inparanoid	1	1.050	225	1.000	Inparanoid score	I2245
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG29207
OrthoDB	1	1.010	-	-		D1387536at2759
OrthoFinder	1	1.000	-	-		FOG0004273
OrthoInspector	1	1.000	-	-		oto17556
orthoMCL	1	0.900	-	-		OOG6_101282
Panther	1	1.100	-	-	LDO	PTHR15680
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2755
SonicParanoid	1	1.000	-	-		X5327
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800