DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8036 and AT2G45290

DIOPT Version :9

Sequence 1:	NP_649812.2	Gene:	CG8036 / 41027	FlyBaseID:	FBgn0037607	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_001324258.1	Gene:	AT2G45290 / 819137	AraportID:	AT2G45290	Length:	741	Species:	Arabidopsis thaliana

Alignment Length:	711	Identity:	190/711 - (26%)
Similarity:	295/711 - (41%)	Gaps:	164/711 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LRIHSINATQASKSGHPTSCASIAEIMSVLFFQQLRLNLKHPRDPSSDRFILSKGHAAPILYAAW 85
            :|..:|:|.:.:|||||......|.:..:|:.:.::.|.|:|...:.|||:||.||...:.||..
plant    88 IRFLAIDAVEKAKSGHPGLPMGCAPMSHILYDEVMKYNPKNPYWFNRDRFVLSAGHGCMLQYALL 152

  Fly    86 AEAGLFPI--ADLNNLRKIDSDLEGHPTPRLNF----IDVGTGSLGQGVAVGAGMAYVGKN---- 140
            ..||...:  .||.:.|:..|...|||.   ||    ::..||.||||:|...|:|...|:
plant   153 HLAGYDSVREEDLKSFRQWGSKTPGHPE---NFETPGVEATTGPLGQGIANAVGLALAEKHLAAR 214

  Fly   141 FDK-----ADYRTYVVVGDGESAEGSIWESLHFAGHYKLDNLCVIFDVNRLGQSEATSLQHKLDV 200
            |:|     .|:.||.::|||...||...|....|||:.|..|...:|.|.:.....|.:.....|
plant   215 FNKPDNEIVDHYTYSILGDGCQMEGISNEVCSLAGHWGLGKLIAFYDDNHISIDGDTDIAFTESV 279

  Fly   201 YRDRLEAFGFNAVVV----DGHDVEELSKAFHCAAITKNKPTAIIAKTFKGRDFPNIEDLDNWHG 261
            .: |.||.|::.:.|    :|:|  |:..|...|....:|||.|...|..|...||..:..:.||
plant   280 DK-RFEALGWHVIWVKNGNNGYD--EIRAAIREAKAVTDKPTLIKVTTTIGYGSPNKANSYSVHG 341

  Fly   262 KPLGDKAAEVVKH-----LEGLIVNKNVKL-----TPKPVPKTGAAPDVDINNIKLSS------P 310
            ..||:|..|..::     .|...|.::||.     ||:     |||.:.|. |.|.::      .
plant   342 AALGEKEVEATRNNLGWPYEPFHVPEDVKSHWSRHTPE-----GAALEADW-NAKFAAYEKKYPE 400

  Fly   311 PAYKLGDSIATRLAYG-------------------------TALAK-----------IGQNNLRV 339
            .|.:|...|:..|..|                         .||||           :..:|:.:
plant   401 EAAELKSIISGELPVGWEKALPTYTPDSPGDATRNLSQQCLNALAKAVPGFLGGSADLASSNMTM 465

  Fly   340 VALDGDTKNSTFSDKLKNLDPQRYIECFIAEQNL-VGV---AVGAACR---RRTVAFVSTFATFF 397
            :...|:.:.:|         |:        |:|| .||   .:||.|.   ..:..|:...||||
plant   466 LKAFGNFQKAT---------PE--------ERNLRFGVREHGMGAICNGIALHSPGFIPYCATFF 513

  Fly   398 T-----RAFDQIRMGAISQTNVNFVGSHCGCSIGEDGPSQMGLEDIAMFRTIPGSTIFYPSDAVS 457
            .     ||  .:|:.|:|:..|.:|.:|....:|||||:...:|.::.||.:|...:|.|:|...
plant   514 VFTDYMRA--AMRISALSEAGVIYVMTHDSIGLGEDGPTHQPIEHLSSFRAMPNIMMFRPADGNE 576

  Fly   458 TERAVELAA---NTKGVCFIRTSR----PNTCVIYDNEEPFTIGRGKVVRQKSSDEVLLIGAGIT 515
            |..|.::|.   .|..|..:...:    |.|.:....:..:||.....   .:..:|:|||.|..
plant   577 TAGAYKIAVTKRKTPSVLALSRQKLPQLPGTSIESVEKGGYTISDNST---GNKPDVILIGTGSE 638

  Fly   516 LYECLAAADQLEKNCITVRVI------------DPF--TVKPLD--AELIIEHGKQCG-GRVVVV 563
            |.....||::|.:...:|||:            |.:  :|.|.|  |.:.||.|...| |::|
plant   639 LEIAAQAAEKLREQGKSVRVVSFVCWELFDEQSDAYKESVLPSDVSARVSIEAGSTFGWGKIV-- 701

  Fly   564 EDHYQQGGLGEAVLSALAGERNFVVKHLYVPTVPRSGPPSVLIDMFGISARHVVNAVNEIL 624
                  ||.|               |.:.:.|...|.|...|...|||:...:|.|...::
plant   702 ------GGKG---------------KSIGIDTFGASAPAGKLYKEFGITIEAMVEAAKSLI 741

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8036	NP_649812.2	PRK05899	8..624	CDD:235639	190/709 (27%)
		TPP_TK	19..270	CDD:238970	86/267 (32%)
		TPP_PYR_DXS_TK_like	324..478	CDD:132916	47/204 (23%)
		Transketolase_C	496..616	CDD:280875	34/136 (25%)
AT2G45290	NP_001324258.1	PLN02790	88..741	CDD:215424	190/709 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	118	1.000	Domainoid score	I1928
eggNOG	1	0.900	-	-		E1_COG0021
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	176	1.000	Inparanoid score	I1482
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354970at2759
OrthoFinder	1	1.000	-	-		FOG0001032
OrthoInspector	1	1.000	-	-		mtm1210
orthoMCL	1	0.900	-	-		OOG6_100329
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730