Protein Alignment CG8036 and tktl2

DIOPT Version :10

• Sequence 1: NP_649812.2
• Gene: CG8036 / 41027
• FlyBaseID: FBgn0037607
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_989227.1
• Gene: tktl2 / 394835
• XenbaseID: XB-GENE-1002824
• Length: 625
• Species: Xenopus tropicalis
• Alignment Length: 620
• Identity: 395/620 - (63%)
• Similarity: 470/620 - (75%)
• Gaps: 4/620 - (0%)

  Fly     2 SYHKPEAKTVQDLKDLAQKLRIHSINATQASKSGHPTSCASIAEIMSVLFFQQLRLNLKHPRDPS 66
            :|.|||.|.:|.|||.|.:||||||.||.||.|||||||.|.||::|||||..:|.....|.:.:
 Frog     3 TYQKPEDKELQALKDAANRLRIHSIRATCASNSGHPTSCCSAAEVLSVLFFNTMRYEAADPGNAN 67

  Fly    67 SDRFILSKGHAAPILYAAWAEAGLFPIADLNNLRKIDSDLEGHPTPRLNFIDVGTGSLGQGVAVG 131
            :|||:||||||||||||||||||....:||.||||||.||||||||:|.|:||.|||||||:...
 Frog    68 NDRFVLSKGHAAPILYAAWAEAGYIKESDLLNLRKIDCDLEGHPTPKLPFVDVATGSLGQGLGAS 132

  Fly   132 AGMAYVGKNFDKADYRTYVVVGDGESAEGSIWESLHFAGHYKLDNLCVIFDVNRLGQSEATSLQH 196
            .||||.||.||||.||.|.::|||||:||::||::.||.||.||||..||||||||||||..|||
 Frog   133 CGMAYTGKYFDKASYRVYCLLGDGESSEGAVWEAMAFASHYHLDNLVAIFDVNRLGQSEAAPLQH 197

  Fly   197 KLDVYRDRLEAFGFNAVVVDGHDVEELSKAFHCAAITKNKPTAIIAKTFKGRDFPNIEDLDNWHG 261
            :.|:|..|.||||:|..|||||||.||..||..||..|:|||||||||:||:....:|:.|||||
 Frog   198 QTDIYMKRCEAFGWNTYVVDGHDVAELCHAFWQAAHVKDKPTAIIAKTYKGKGISGVENEDNWHG 262

  Fly   262 KPL-GDKAAEVVKHLEGLIVNKNVKLTPKPVPKTGAAPDVDINNIKLSSPPAYKLGDSIATRLAY 325
            ||: .|||..::..::..| ..|.||:|. || ...||.:.|::|...|||.||:||.||||.||
 Frog   263 KPMPKDKAESIINEIQSQI-QTNRKLSPL-VP-IADAPKISISDITFPSPPNYKIGDKIATRRAY 324

  Fly   326 GTALAKIGQNNLRVVALDGDTKNSTFSDKLKNLDPQRYIECFIAEQNLVGVAVGAACRRRTVAFV 390
            |.||||:|..|.||:||||||||||||:..|...|.|||||||||||:|.||:|.|.|.|||||.
 Frog   325 GLALAKLGHANSRVIALDGDTKNSTFSEIFKKEHPDRYIECFIAEQNMVSVAMGCATRNRTVAFA 389

  Fly   391 STFATFFTRAFDQIRMGAISQTNVNFVGSHCGCSIGEDGPSQMGLEDIAMFRTIPGSTIFYPSDA 455
            ||||.|.:||:|.||||||||:|||..|||||.||||||||||.|||:||||.||..|:|||||.
 Frog   390 STFAAFLSRAYDHIRMGAISQSNVNLCGSHCGVSIGEDGPSQMALEDLAMFRAIPTCTVFYPSDG 454

  Fly   456 VSTERAVELAANTKGVCFIRTSRPNTCVIYDNEEPFTIGRGKVVRQKSSDEVLLIGAGITLYECL 520
            ||||.||.|||||.|:||||||||:|.|||..:|.|.||:.|||||.|||.|.:||||:||:|.|
 Frog   455 VSTEHAVFLAANTPGICFIRTSRPDTAVIYSPDEKFEIGQAKVVRQSSSDRVTVIGAGVTLHEAL 519

  Fly   521 AAADQLEKNCITVRVIDPFTVKPLDAELIIEHGKQCGGRVVVVEDHYQQGGLGEAVLSALAGERN 585
            ||||:|.|..|.:||:||||:|||||..|:..|:..||.::.|||||::|||||||.:|:|||..
 Frog   520 AAADELAKQGINIRVVDPFTIKPLDAATILSSGRATGGHIITVEDHYREGGLGEAVCAAVAGEPG 584

  Fly   586 FVVKHLYVPTVPRSGPPSVLIDMFGISARHVVNAV 620
            |:|:.|.|..|||||.|:.|:|:||||:|.:|.||
 Frog   585 FIVQTLAVRGVPRSGKPTELLDLFGISSRCIVEAV 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8036	NP_649812.2	PRK05899	8..624	CDD:235639	391/614 (64%)
tktl2	NP_989227.1	PRK05899	9..621	CDD:235639	391/614 (64%)