Protein Alignment CG8036 and tkt-1

DIOPT Version :9

• Sequence 1: NP_649812.2
• Gene: CG8036 / 41027
• FlyBaseID: FBgn0037607
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_501878.1
• Gene: tkt-1 / 177906
• WormBaseID: WBGene00008506
• Length: 618
• Species: Caenorhabditis elegans
• Alignment Length: 609
• Identity: 375/609 - (61%)
• Similarity: 453/609 - (74%)
• Gaps: 5/609 - (0%)

  Fly    13 DLKDLAQKLRIHSINATQASKSGHPTSCASIAEIMSVLFFQQLRLNLKHPRDPSSDRFILSKGHA 77
            ||:|.|.::||.||..|.|||||||||..|.|||||.|||.:::.::..|:..|:|||:||||||
 Worm    10 DLEDAANRMRISSIEMTCASKSGHPTSSTSAAEIMSTLFFSEMKYDVAEPKSASADRFVLSKGHA 74

  Fly    78 APILYAAWAEAGLFPIADLNNLRKIDSDLEGHPTPRLNFIDVGTGSLGQGVAVGAGMAYVGKNFD 142
            .|||||||.||||.....:.:|||||||:|||||||||||||.|||||||:.|..|||||||..|
 Worm    75 CPILYAAWEEAGLLSHEQVLSLRKIDSDIEGHPTPRLNFIDVATGSLGQGLGVATGMAYVGKYID 139

  Fly   143 KADYRTYVVVGDGESAEGSIWESLHFAGHYKLDNLCVIFDVNRLGQSEATSLQHKLDVYRDRLEA 207
            ||.||.:.::|||||||||:||:..||..||||||..|.||||||||:||||.|.::.|:.|..|
 Worm   140 KASYRVFCLLGDGESAEGSVWEAAAFASIYKLDNLVAIVDVNRLGQSQATSLGHDVETYKARFAA 204

  Fly   208 FGFNAVVVDGHDVEELSKAFHCAAITKNKPTAIIAKTFKGRDFPNIEDLDNWHGKPLGDKAAEVV 272
            |||||::|:||:|:||..|:..|..||.|||||||||.||:....||:.|||||||:.:.....:
 Worm   205 FGFNAIIVNGHNVDELLAAYETARSTKGKPTAIIAKTLKGKGIEGIENEDNWHGKPVPEGTVNAI 269

  Fly   273 K-HLEGLIVNKNVKLTPKPVPKTGAAPDVDINNIKLSSPPAYKLGDSIATRLAYGTALAKIGQNN 336
            | ...|  ..|...:..||: ....|.|:.:.:||::: |.||.||.:|||.||||||||:|..:
 Worm   270 KARFHG--SQKGKLVAQKPI-NDAPAIDLHVGSIKMAA-PEYKKGDKVATRAAYGTALAKLGDAS 330

  Fly   337 LRVVALDGDTKNSTFSDKLKNLDPQRYIECFIAEQNLVGVAVGAACRRRTVAFVSTFATFFTRAF 401
            .||:.||||||||||||||....|.::|||||||||||||||||.||.||:.|.||||.|||||.
 Worm   331 PRVIGLDGDTKNSTFSDKLLKKHPDQFIECFIAEQNLVGVAVGAQCRDRTIPFTSTFAAFFTRAT 395

  Fly   402 DQIRMGAISQTNVNFVGSHCGCSIGEDGPSQMGLEDIAMFRTIPGSTIFYPSDAVSTERAVELAA 466
            |||||.|:|..|:..||||.|.||||||||||.|||:|:||||||:|:|||:||||.|||.||||
 Worm   396 DQIRMAAVSFANLKCVGSHVGVSIGEDGPSQMALEDLAIFRTIPGATVFYPTDAVSAERATELAA 460

  Fly   467 NTKGVCFIRTSRPNTCVIYDNEEPFTIGRGKVVRQKSSDEVLLIGAGITLYECLAAADQLEKNCI 531
            |||||.||||.||...|:|||||||.||:.|||:|.:.|:::|:|:|:||||.|.||::|||..|
 Worm   461 NTKGVVFIRTGRPALPVLYDNEEPFHIGQAKVVKQSAQDKIVLVGSGVTLYESLKAAEELEKEGI 525

  Fly   532 TVRVIDPFTVKPLDAELIIEHGKQCGGRVVVVEDHYQQGGLGEAVLSALAGERNFVVKHLYVPTV 596
            ...||||||:||||.:.|.||..:.|||||..||||..||:||||.:|||......|:.|.|..|
 Worm   526 HATVIDPFTIKPLDGKTIAEHALKVGGRVVTTEDHYAAGGIGEAVSAALADYPTIRVRSLNVKEV 590

  Fly   597 PRSGPPSVLIDMFGISARHVVNAV 620
            ||||||..|:||:||||||:|.||
 Worm   591 PRSGPPDALVDMYGISARHIVAAV 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8036	NP_649812.2	PRK05899	8..624	CDD:235639	375/609 (62%)
		TPP_TK	19..270	CDD:238970	156/250 (62%)
		TPP_PYR_DXS_TK_like	324..478	CDD:132916	114/153 (75%)
		Transketolase_C	496..616	CDD:280875	68/119 (57%)
tkt-1	NP_501878.1	PRK05899	9..615	CDD:235639	375/609 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162508
Domainoid	1	1.000	329	1.000	Domainoid score	I621
eggNOG	1	0.900	-	-		E1_COG0021
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69456
Inparanoid	1	1.050	740	1.000	Inparanoid score	I303
Isobase	1	0.950	-	0	Normalized mean entropy	S1450
OMA	1	1.010	-	-		QHG58668
OrthoDB	1	1.010	-	-		D159833at33208
OrthoFinder	1	1.000	-	-		FOG0001032
OrthoInspector	1	1.000	-	-		otm14411
orthoMCL	1	0.900	-	-		OOG6_100329
Panther	1	1.100	-	-	LDO	PTHR43195
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1527
SonicParanoid	1	1.000	-	-		X1857
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790