DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8032 and paox1

DIOPT Version :9

Sequence 1:	NP_001262380.1	Gene:	CG8032 / 41026	FlyBaseID:	FBgn0037606	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001107075.1	Gene:	paox1 / 564675	ZFINID:	ZDB-GENE-081104-436	Length:	490	Species:	Danio rerio

Alignment Length:	529	Identity:	161/529 - (30%)
Similarity:	245/529 - (46%)	Gaps:	76/529 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 IVIIGAGMAGLSAANHLLQNGCDDFLILEARGRVGGRIVSIPLSNNQKIELGANWIHGVL-GNPI 105
            ||::|||:|||:||..|.:.|.:|..:|||...||||:.:..| .|..::.||.:|||.. .||:
Zfish     8 IVVVGAGVAGLAAAKKLKEYGFNDVTVLEAAENVGGRVATATL-GNACVDTGAQYIHGTSEKNPV 71

  Fly   106 FELAVQHGLVSVVNVPKPHKVVATTEDGHQVPFNILQEIYEAYVCFLRRCDEYFLCQYSPPPDIH 170
            :  .:..||::  .:|:..:.......||:|..|..:..||.        .|.|:..........
Zfish    72 Y--CLLKGLLN--QLPEMGEEAFYNNKGHKVNANFARRAYEH--------GESFIYHRGSGNSGK 124

  Fly   171 SVGEHINYEIEIYLSGVQDPKEKRLKQSIFNCLLKRETCITGCNNMDEVDLLELGSYTELQGGNI 235
            |:|||...:.:..:..:|:.::.|: ||:|..:.|......|.:::..:.|.....|.::  |:.
Zfish   125 SLGEHYAVKTQGVIERLQEDEKARM-QSVFALVGKDMLIDIGASDLHRISLDSWQYYIDM--GDS 186

  Fly   236 VLPTGYS-SILRPLGAQIAKQSILTKCPVKKIHWKRKKTFTGLETVDENSEDEHSDDSERTVTEV 299
            |..||:. .::..|.....|..:|.|..|:.|.|            |.:.....::.|
Zfish   187 VNITGFMYQLVDLLKEDFPKDRLLLKREVRTIKW------------DGSFPSPQNEAS------- 232

  Fly   300 PTGEIRGASVESNTSSNCDYPAGNVRIDCEDGRVFHAAHVICTIPLGVLKNTHRTLFDPVLPQYK 364
            |.|::|            .||   |.|.||||....|.|||.|:.||.||.....||.|.||..|
Zfish   233 PEGKVR------------QYP---VCIVCEDGEEILADHVIVTVSLGCLKAQASDLFIPSLPTEK 282

  Fly   365 QESIENLMFGTVDKIFLEYERPFLSADISEIMLLWDDDKRDMNSSEEELASEAYLSKN---WFKK 426
            .|.|..|.||.:.||||.||..|...|:..|..:::||            :.|.:|.|   |.|.
Zfish   283 IEVINKLCFGNIAKIFLAYEEAFWENDVGSISFIYEDD------------TPASISTNKMQWLKS 335

  Fly   427 IYSFAKVT-----DTLLLGWVSGREAEYMEKLDHEAVAEKCTEILRNFL-QDPYVPKPKRCVCTS 485
            :.||:.:.     ..:|:||..|..|:.:|.:....::...|:.|:.|. ....:|:||..:||.
Zfish   336 MQSFSVLRPKERFGNVLIGWCPGEIADLVETMTDNELSAAVTDHLKMFFGPSANIPQPKSILCTK 400

  Fly   486 WKSQDFTGGAYTSIPVGATQEDIENLAQPLYAT--PQAMKPAIVFAGEHTHSSFYSTVHGAYLSG 548
            |:|..|..|:||.:|||...:.::.|||||..:  |.| ...::||||.|..:.|.||.||.|||
Zfish   401 WRSNKFIKGSYTFLPVGVDGQVMDTLAQPLEGSQFPDA-HLQVMFAGEATMKTLYGTVQGALLSG 464

  Fly   549 RTAAQHLLA 557
            ...|..|.|
Zfish   465 HREADRLAA 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8032	NP_001262380.1	NAD_binding_8	44..104	CDD:290186	25/60 (42%)
CG8032	NP_001262380.1	Amino_oxidase	49..556	CDD:279874	154/519 (30%)
paox1	NP_001107075.1	Amino_oxidase	22..471	CDD:279874	149/511 (29%)
paox1	NP_001107075.1	NAD_binding_8	<24..78	CDD:290186	19/56 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583689
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48501
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.820