DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8032 and si:ch211-127i16.2

DIOPT Version :9

Sequence 1:	NP_001262380.1	Gene:	CG8032 / 41026	FlyBaseID:	FBgn0037606	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_021327915.1	Gene:	si:ch211-127i16.2 / 558050	ZFINID:	ZDB-GENE-091204-54	Length:	523	Species:	Danio rerio

Alignment Length:	598	Identity:	120/598 - (20%)
Similarity:	214/598 - (35%)	Gaps:	207/598 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 IVIIGAGMAGLSAANHL-LQNGCDDFLILEARGRVGGRIVS--IPLSNN-QKIELGANW-----I 97
            :|::|||::|||||..| .:|.....|:||||.|||||.||  :|.:|. ::.::|..|     |
Zfish     8 VVVVGAGLSGLSAARRLQKRNPRLSVLVLEARDRVGGRTVSEDLPAANGVEQWDMGGQWVSSSQI 72

  Fly    98 HGVLGNPIFELAVQHGLVSVVNVPKPHKVVATTEDGHQVPFNILQEIYEAYVCFLRRCDEYFLCQ 162
            |      :.||..:.|:                            |::               .|
Zfish    73 H------VMELIKEFGV----------------------------EVF---------------TQ 88

  Fly   163 YSPPPDIHSVGEHINYEIEIYLS---------------------------GVQDPKEKR------ 194
            |:....:|.:|.. |.:|::|.:                           .|:||....
Zfish    89 YTEGKKVHHIGGP-NAKIKMYNTTVPQFSPLVMLDFIQVMWKVDKLTKTISVEDPMSSPNAELYD 152

  Fly   195 -------LKQSIFNCLLKRETCITGCNNM------DEVDLLELGSYTELQGGNI-VLPT--GYSS 243
                   ::|:|:...:|.|..:  |:.:      .::..|....|:...||.: :|.|  |...
Zfish   153 SMTLYTFMEQNIWTKDIKEELAV--CSRIVFGLETSQISFLFFLLYSAAAGGTLRLLETSPGSGQ 215

  Fly   244 ILRPLGAQIAKQSILTKCPVKKIHWKRKKTFTGLETVDENSEDEHSDDSERTVTEVPTGEIRGAS 308
            ..|..|.  .:|  |:|..|::|...|.:....:..:.::||
Zfish   216 EFRVKGG--TQQ--LSKMLVEQIGSDRVRLGAAVTAICQDSE----------------------- 253

  Fly   309 VESNTSSNCDYPAGNVRIDCEDGRVFHAAHVICTIPLGVLKNTHRTLFDPVLPQYKQESIENLMF 373
                          |:::....|.|...| ||...|..:....|   ::|.||..:|..|::|..
Zfish   254 --------------NIKVTTSAGTVSCKA-VIVACPSHLAAQIH---YEPPLPSERQRLIQSLPM 300

  Fly   374 GTVDKIFLEYERPFL--SADISEIMLLWDDDKRDMNSSEEELASEAYLSKNWFKKIYSFAKVTDT 436
            |.:.|..:.|...|.  .....||::      |...|....:..:|...|.            :.
Zfish   301 GHMTKFIITYPTAFWREKGFSGEIVV------RPSESCPLSVTFDATSPKG------------NP 347

  Fly   437 LLLGWVSGREA-EYMEKLDHEAVAEKCTEILRNFLQ------DPYVPKPKRCVCTSWKSQDFTGG 494
            .|:|:::|.:| ::.:|    .:.|:...::.:.::      ..|:...::    .|..:.::||
Zfish   348 ALVGFITGIQARDWCDK----KLEERRDAVISSLVKYLGPEASTYIHYAEK----DWGKEQYSGG 404

  Fly   495 AYTSIPVGATQEDIENLAQPLYAT---PQAMKPA--IVFAGEHTHSSFYSTVHGAYLSGRTAAQH 554
            .    ||        |:..|...|   |...||.  |.:||..|.:.:...:.||..:|:.||..
Zfish   405 C----PV--------NVMTPGMLTFYHPSLRKPCGRIHWAGTETATIWCGYLDGAVQAGQRAAME 457

  Fly   555 LLASDEPDEIIME 567
            :||...|..:..|
Zfish   458 VLAQLCPSSLSRE 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8032	NP_001262380.1	NAD_binding_8	44..104	CDD:290186	28/68 (41%)
CG8032	NP_001262380.1	Amino_oxidase	49..556	CDD:279874	112/578 (19%)
si:ch211-127i16.2	XP_021327915.1	Amino_oxidase	15..459	CDD:307636	112/578 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583710
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840