Protein Alignment CG8032 and MAOB

DIOPT Version :9

• Sequence 1: NP_001262380.1
• Gene: CG8032 / 41026
• FlyBaseID: FBgn0037606
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_000889.3
• Gene: MAOB / 4129
• HGNCID: 6834
• Length: 520
• Species: Homo sapiens
• Alignment Length: 591
• Identity: 127/591 - (21%)
• Similarity: 206/591 - (34%)
• Gaps: 172/591 - (29%)

  Fly    42 IVIIGAGMAGLSAANHLLQNGCDDFLILEARGRVGGRIVSIPLSNNQK---IELGANWIHGVLGN 103
            :|::|.|::|::||..|..:|. :.::||||.|||||..::   .|||   ::||.::: |...|
Human     7 VVVVGGGISGMAAAKLLHDSGL-NVVVLEARDRVGGRTYTL---RNQKVKYVDLGGSYV-GPTQN 66

  Fly   104 PIFELAVQHGLVSVVNVPKPHKVVATTEDGHQVPFN-----ILQEI-YEAYVCFLRRCDEYFLCQ 162
            .|..||.:.|| ....|.:..:::...: |...||.     :...| |..:..|.|..|:
Human    67 RILRLAKELGL-ETYKVNEVERLIHHVK-GKSYPFRGPFPPVWNPITYLDHNNFWRTMDD----- 124

  Fly   163 YSPPPDIHSVGEHINYEIEIYLSGVQDPKEKRLKQSIFNCLLKR-------------------ET 208
                     :|..|..:.         |.:..|.:...|..:|.                   ..
Human   125 ---------MGREIPSDA---------PWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNL 171

  Fly   209 CITGCNNMDEVDLLELGSYTELQGG--NIVLPTGYSSILRPLGAQIAKQSILTKCPVKKIHWKRK 271
            |:|.  ...||..|....|.:..||  .|:..|.        |.|                  .:
Human   172 CVTA--ETHEVSALWFLWYVKQCGGTTRIISTTN--------GGQ------------------ER 208

  Fly   272 KTFTGLETVDENSEDEHSDDSERTVTEVPTGEIRGASVESNTSSNCDYPAGNVRIDCEDGRVFHA 336
            |...|...|.|...|...|   |...|.|...|             |....||.::..:..::.|
Human   209 KFVGGSGQVSERIMDLLGD---RVKLERPVIYI-------------DQTRENVLVETLNHEMYEA 257

  Fly   337 AHVICTIPLGVLKNTHRTLFDPVLPQYKQESIENLMFGTVDKIFLEYERPFLSADISEIMLLWDD 401
            .:||..||..:....|   |:|.||..:.:.|..:..|:|.|..:.|:.||
Human   258 KYVISAIPPTLGMKIH---FNPPLPMMRNQMITRVPLGSVIKCIVYYKEPF-------------- 305

  Fly   402 DKRDMNSSEEELASEAYLSKNWFKKIYSFAKVTD--------TL-----------LLGWVSGREA 447
                                 |.||.|....:.|        ||           ::|::...:|
Human   306 ---------------------WRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKA 349

  Fly   448 EYMEKLDHEAVAEKCTEILRNFLQDPYVPKPKRCVCTSWKSQDFTGGAYTS-IPVGATQEDIENL 511
            ..:.:|..|...:|..|:....|......:|......:|..:.::||.||: .|.|...:....|
Human   350 RKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVL 414

  Fly   512 AQPLYATPQAMKPAIVFAGEHTHSSFYSTVHGAYLSGRTAAQHLL--ASDEPDEIIMESDGSDLS 574
            .||:        ..|.|||..|.:.:...:.||..:|..||:.:|  ....|::.|.:|:...:.
Human   415 RQPV--------DRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVD 471

  Fly   575 AWIQGI 580
            ...|.|
Human   472 VPAQPI 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8032	NP_001262380.1	NAD_binding_8	44..104	CDD:290186	22/62 (35%)
		Amino_oxidase	49..556	CDD:279874	118/556 (21%)
MAOB	NP_000889.3	Amino_oxidase	14..451	CDD:396255	118/556 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149557
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840