Protein Alignment CG8032 and MAOA

DIOPT Version :9

• Sequence 1: NP_001262380.1
• Gene: CG8032 / 41026
• FlyBaseID: FBgn0037606
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_000231.1
• Gene: MAOA / 4128
• HGNCID: 6833
• Length: 527
• Species: Homo sapiens
• Alignment Length: 568
• Identity: 126/568 - (22%)
• Similarity: 209/568 - (36%)
• Gaps: 134/568 - (23%)

  Fly    42 IVIIGAGMAGLSAANHLLQNGCDDFLILEARGRVGGRIVSIPLSNNQKIELGANWIHGVLGNPIF 106
            :|:||.|::|||||..|.:.|. ..|:||||.|||||..:|...:...:::|..:: |...|.|.
Human    16 VVVIGGGISGLSAAKLLTEYGV-SVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYV-GPTQNRIL 78

  Fly   107 ELAVQHGLVSV-VNVPKPHKVVATTEDGHQVPFN-----ILQEI-YEAYVCFLRRCDEYFLCQYS 164
            .|:.:.|:.:. |||.:  ::|...: |...||.     :...| |..|....|..|.   ....
Human    79 RLSKELGIETYKVNVSE--RLVQYVK-GKTYPFRGAFPPVWNPIAYLDYNNLWRTIDN---MGKE 137

  Fly   165 PPPDIHSVGEHINYEIEIYLSGVQDPKEKRLKQSIFNCLLKRETC---------ITGCNNMDEVD 220
            .|.|.....:|            .|..:|...:.:.:.:...:|.         |...:...||.
Human   138 IPTDAPWEAQH------------ADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVS 190

  Fly   221 LLELGSYTELQGGNIVLPTGYSSILRPLGAQIAKQSILTKCPVKKIHWKRKKTFTGLETVDENSE 285
            .|....|.:..||.    |...|:..  |.|                   ::.|.|
Human   191 ALWFLWYVKQCGGT----TRIFSVTN--GGQ-------------------ERKFVG--------- 221

  Fly   286 DEHSDDSERTVTEVPTGEIRGASVESN-TSSNCDYPAGNVRIDCEDGRVFHAAHVICTIPLGVLK 349
             .....|||.:      ::.|..|:.| ..::.|..:.|:.|:..:...:...:||..||..:..
Human   222 -GSGQVSERIM------DLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTA 279

  Fly   350 NTHRTLFDPVLPQYKQESIENLMFGTVDKIFLEYERPF-LSADISEIMLLWDDDKRDMNSSEEEL 413
            ..|   |.|.||..:.:.|:.|..|.|.|..:.|:..| ...|....|::.|:|
Human   280 KIH---FRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDED----------- 330

  Fly   414 ASEAYLSKNWFKKIYSFAKVTDTL-----------LLGWVSGREAEYMEKLDHEAVAEKCTEILR 467
                             |.::.||           ::|::..|:|:.:.||..|...:|..|:..
Human   331 -----------------APISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYA 378

  Fly   468 NFLQDPYVPKPKRCVCTSWKSQDFTGGAYTS-IPVGATQEDIENLAQPLYATPQAMKPAIVFAGE 531
            ..|.......|......:|..:.::||.||: .|.|...:....:.||:        ..|.|||.
Human   379 KVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPV--------GRIFFAGT 435

  Fly   532 HTHSSFYSTVHGAYLSGRTAAQHLLAS----DEPDEIIMESDGSDLSA 575
            .|.:.:...:.||..:|..||:.:|..    .|.|..:.|.:..|:.|
Human   436 ETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPA 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8032	NP_001262380.1	NAD_binding_8	44..104	CDD:290186	23/59 (39%)
		Amino_oxidase	49..556	CDD:279874	116/536 (22%)
MAOA	NP_000231.1	YobN	15..460	CDD:224152	120/543 (22%)
		Interaction with membrane phospholipid headgroups. /evidence=ECO:0000305	520..522

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149526
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840