DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8032 and CG10561

DIOPT Version :9

Sequence 1:	NP_001262380.1	Gene:	CG8032 / 41026	FlyBaseID:	FBgn0037606	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_476608.1	Gene:	CG10561 / 35189	FlyBaseID:	FBgn0002036	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	564	Identity:	161/564 - (28%)
Similarity:	249/564 - (44%)	Gaps:	128/564 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 GDQ---PQTSGNNTNVKIVIIGAGMAGLSAANHLLQNGCDDFLILEARGRVGGRIVSIPLSNNQK 89
            ||:   |.......|.:||::|||:||||||.|||.:|....:||||..|.||||      |.|:
  Fly    24 GDKQRSPDLEAARQNTQIVVVGAGLAGLSAAQHLLSHGFRRTVILEATDRYGGRI------NTQR 82

  Fly    90 I-----ELGANWIHGVLG--NPIFELAVQ-HGLVSVVNVPKPHKVVAT-TEDGHQVPFNILQEIY 145
            .     ||||.|:. :.|  :.::||... .||...:..|..    || .:||.::...:::.|
  Fly    83 FGDTYCELGAKWVK-IDGSQDSMYELLRNTEGLGKQIKQPDR----ATYLQDGSRINPAMVELI- 141

  Fly   146 EAYVCFLRRCDEYF--LC-------QYSPPPDIHSVGEHINY----EIEIYLSGVQDPKEKRLKQ 197
                      |..|  ||       :.....|:||:...:||    ...|.....|.||::...:
  Fly   142 ----------DTLFRQLCRGFKVSERVKTGGDLHSLDNVMNYFRTESDRIIGVSFQHPKDQLAAR 196

  Fly   198 SIFNCLLKRETCITGCNNMDEVDLLELGSYTELQGGNIVLPTGYSSILRPLGAQIAKQSILTKCP 262
            .||..|.|....|.||       .||   |..::.                         :||||
  Fly   197 EIFQSLFKEFGSILGC-------CLE---YVNIEH-------------------------ITKCP 226

  Fly   263 VKKIHWKRKKTF--TGLE-TVDENSEDEHSDDSERTVTEVPTGEIRGASVESNTSSNCDYPAGNV 324
            |::   :::..:  |||: .||:..::.   |..:..|..|.|:|:..            ||...
  Fly   227 VQQ---EQRPLYVPTGLDNVVDDLIQNM---DKAQLQTGKPVGQIQWT------------PAPMK 273

  Fly   325 RIDCEDGRVFHAAHVICTIPLGVLKNTHRTLFDPVLPQYKQESIENLMFGTVDKIFLEYERP--- 386
            .:.|.||.:::|.|:|||:||||||:....||.|.||..|..:|.||.||...||:|.|::|
  Fly   274 SVGCLDGSLYNADHIICTLPLGVLKSFAGVLFRPTLPLDKMLAIRNLGFGNPLKIYLSYKKPIGR 338

  Fly   387 FLSADISEIMLLWDDDKRDMNSSEEELASEAYLSKNWFKKIYSFAKVTDT--LLLGWVSGREAEY 449
            :|...:..:..|       :|.|.|:..     .:||.:::...::|..:  :|...|.|...|.
  Fly   339 WLKGSLRPLGTL-------LNPSVEQQP-----ERNWTQQVVEISQVPSSQHVLEVHVGGGYYEE 391

  Fly   450 MEKLDHEAVAEKCTEILRNFLQDPYVPKPKRCVCTSWK-SQDFTGG-AYTSIPVGATQEDIENLA 512
            :|||..|.:.|:.|.:||..:....||.|:..:.::|. |..:.|| .|.|  ..::..|::.||
  Fly   392 IEKLPDEELLEQITGLLRRCVSSHLVPYPQELLRSNWSTSACYLGGRPYFS--TNSSARDVQRLA 454

  Fly   513 QPLYATPQAMKPAIVFAGEHTHSSFYSTVHGAYLSGRTAAQHLL 556
            .||    ....|.::|||:.|....:.|:..|..||...||.::
  Fly   455 APL----GEKSPGLLFAGDATSLRGFGTIDAARSSGIREAQRII 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8032	NP_001262380.1	NAD_binding_8	44..104	CDD:290186	30/66 (45%)
CG8032	NP_001262380.1	Amino_oxidase	49..556	CDD:279874	152/538 (28%)
CG10561	NP_476608.1	NAD_binding_8	43..109	CDD:290186	32/72 (44%)
CG10561	NP_476608.1	Amino_oxidase	48..494	CDD:279874	152/538 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441197
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	1	1.000	-	-		otm46708
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850