DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8032 and zgc:66484

DIOPT Version :9

Sequence 1:	NP_001262380.1	Gene:	CG8032 / 41026	FlyBaseID:	FBgn0037606	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_005167974.1	Gene:	zgc:66484 / 327557	ZFINID:	ZDB-GENE-030131-5768	Length:	524	Species:	Danio rerio

Alignment Length:	544	Identity:	185/544 - (34%)
Similarity:	279/544 - (51%)	Gaps:	84/544 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 NVKIVIIGAGMAGLSAANHLLQNGCDDFLILEARGRVGGRI-VSIPLSNNQKIELGANWIHGVLG 102
            |.|:::||:|.|||:||:.|::.|.:|.|:|||:.|||||: .:.|.:.| .||:|||||||..|
Zfish    36 NAKVLVIGSGFAGLAAASKLIEAGFEDVLVLEAKERVGGRVHTTKPFTEN-IIEVGANWIHGQKG 99

  Fly   103 NPIFELAVQHGLVS-----VVNVPKPHKVVAT----TEDGHQVPFNILQEIYEAYVC--FLRRCD 156
            ||::::|.:..|:|     :.|:..||.|...    .|||..||.:::.:     ||  |.:..|
Zfish   100 NPLYKIAKEKNLLSEGPSAMKNMCLPHSVSPRDYFFNEDGKPVPKSVVDQ-----VCARFSKLTD 159

  Fly   157 EYFLCQYSPPPDIHSVGEHINYEIEIYL----SGVQDPKEKRLKQSIFNCLLKRETCI-TGCNNM 216
            :.|        |....|::....:..||    .|.:..|.:..:|....|  ||..|. ..|:::
Zfish   160 KAF--------DDELDGKYRKLTLGAYLDDAFGGTELSKTEDARQVYEWC--KRVECTDEACSSL 214

  Fly   217 DEVDLLELGSYTELQGG--NIVLPTGYSSILRPLGAQIAKQSILTKCPVKKIHWKRKKTFTGLET 279
            .|:...:|.:||||:||  |.:.|.||.:||..|...:..:::....|||.|.|         :.
Zfish   215 YEISASQLSNYTELEGGFFNTLGPGGYQAILDVLLRDVPSEAVRCNAPVKTIRW---------DL 270

  Fly   280 VDENSEDEHSDDSERTVTEVPTGEIRGASVESNTSSNCDYPAGNVRIDCEDGRVFHAAHVICTIP 344
            |.|...:|.                             |:|   |::.||:|:.|.|.|||.|:.
Zfish   271 VKEGQSEEE-----------------------------DHP---VQVVCENGQTFEADHVIVTVS 303

  Fly   345 LGVLKNTHRTLFDPVLPQYKQESIENLMFGTVDKIFLEYERPFLSADISEIMLLWDDDKRDMNSS 409
            |||||...:|:|||.||:.|..:|.:|.||.|:||||.:|:.|...|.:.:.|:|.:...|.:..
Zfish   304 LGVLKEHAKTMFDPTLPEKKLSAINDLGFGIVNKIFLFFEKSFWPDDCAGVQLVWKEGPEDKDVY 368

  Fly   410 EEELASEAYLSKNWFKKIYSFAKVT--DTLLLGWVSGREAEYMEKLDHEAVAEKCTEILRNFLQD 472
            |:....|.: .:.|||||..|..|.  .|.|.||::||||.|||.|....:.|.|..:||:....
Zfish   369 EDLSEGEDW-KQTWFKKITGFDTVARHPTALCGWITGREALYMESLQDREIQEVCVRLLRSSTGW 432

  Fly   473 PYVPKPKRCVCTSWKSQDFTGGAYTSIPVGAT-QEDIENLAQPL---YATPQAMKPAIVFAGEHT 533
            | ||:..:.:.:.|.|.....|:||.:|.|.. .|..:.||.||   :.:.......::||||.|
Zfish   433 P-VPEVSKTLISRWGSDPQVRGSYTFVPDGVDGVEAHKALASPLPPKHRSRGRKNLQVLFAGEAT 496

  Fly   534 HSSFYSTVHGAYLSGRTAAQHLLA 557
            |.:||:|.|||||||:..|:.|::
Zfish   497 HVNFYTTTHGAYLSGQREAERLIS 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8032	NP_001262380.1	NAD_binding_8	44..104	CDD:290186	32/60 (53%)
CG8032	NP_001262380.1	Amino_oxidase	49..556	CDD:279874	179/531 (34%)
zgc:66484	XP_005167974.1	PLN02568	37..522	CDD:215308	184/543 (34%)
zgc:66484	XP_005167974.1	NAD_binding_8	41..101	CDD:290186	32/60 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583697
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48501
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	1	1.000	-	-		otm24246
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	1	1.100	-	-	O	PTHR10742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.720