Protein Alignment CG8032 and KDM1B

DIOPT Version :9

• Sequence 1: NP_001262380.1
• Gene: CG8032 / 41026
• FlyBaseID: FBgn0037606
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_016865929.1
• Gene: KDM1B / 221656
• HGNCID: 21577
• Length: 832
• Species: Homo sapiens
• Alignment Length: 568
• Identity: 135/568 - (23%)
• Similarity: 222/568 - (39%)
• Gaps: 127/568 - (22%)

  Fly    15 TEEGMANIG--SAGAGDQPQTSGNNTNVKIVIIGAGMAGLSAANHLLQNGCDDFLILEARGRVGG 77
            |.:|:.|.|  |.|| ||.....:..|..::|||||.|||:||..|...|. ...:|||:.|:||
Human   366 TRKGLINTGVLSVGA-DQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGI-KVTVLEAKDRIGG 428

  Fly    78 RIVSIPLSNNQKIELGANWIHGVLGNPIFELAVQHGLVSVVNVPKPHKVVATTEDGHQVP----- 137
            |:..........:..||..::|.:.||:..:..|.|    :::.|..:.....::|.::.
Human   429 RVWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQLG----ISMHKFGERCDLIQEGGRITDPTID 489

  Fly   138 ------FNILQEIYEAYVCFLRRCDEYFLCQYSPPPDIHSVGEHIN--YEIEIYLSGVQDPKEKR 194
                  ||.|.::...:     |.|:   .|....|    :||.|.  |:..|..||:|   ...
Human   490 KRMDFHFNALLDVVSEW-----RKDK---TQLQDVP----LGEKIEEIYKAFIKESGIQ---FSE 539

  Fly   195 LKQSIFNCLLKRETCITGCNNMDEV-----DLLELGSYTELQGGNIVLPTGYSSILRPL--GAQI 252
            |:..:....|.......| :|:.:|     |..|.  :.:..|.:.:|..|||.|:..|  |..|
Human   540 LEGQVLQFHLSNLEYACG-SNLHQVSARSWDHNEF--FAQFAGDHTLLTPGYSVIIEKLAEGLDI 601

  Fly   253 AKQSILTKCPVKKIHWKRKKTFTGLETVDENSEDEHSDDSERTVTEVPTGEIRGASVESNTSSNC 317
            ..:|...:|                                                       .
Human   602 QLKSPQVQC-------------------------------------------------------I 611

  Fly   318 DYPAGNVRIDCEDGRVFHAAHVICTIPLGVLKNTHRTLFDPVLPQYKQESIENLMFGTVDKIFLE 382
            ||....|::...||..:.|..|:.|:||.:|:. ....|:|.|.:.|.::|.:|..|.::||.|:
Human   612 DYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQK-GAIQFNPPLSEKKMKAINSLGAGIIEKIALQ 675

  Fly   383 YERPFLSADISEIMLLWDDDKR--DMNSSEEELASEAYLSKNWFKKIYSF-AKVTDTLLLGWVSG 444
            :...|           ||...:  |........||:    :..|...|.. .:...::|:..::|
Human   676 FPYRF-----------WDSKVQGADFFGHVPPSASK----RGLFAVFYDMDPQKKHSVLMSVIAG 725

  Fly   445 REAEYMEKLDHEAVAEKCTEILRNFLQDPYVPKPKRCVCTSWKSQDFTGGAYTSIPVGATQEDIE 509
            .....:..||.:.|.::|...||...::..||.|.:...|.|.:..:...||:.:..|.:.|..:
Human   726 EAVASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYD 790

  Fly   510 NLAQPLYATPQAMKPAIVFAGEHTHSSFYSTVHGAYLSGRTAAQHLLA 557
            .:|:.:..|       :.||||.|:..|..||.||||||...|..:.|
Human   791 IIAEDIQGT-------VFFAGEATNRHFPQTVTGAYLSGVREASKIAA 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8032	NP_001262380.1	NAD_binding_8	44..104	CDD:290186	22/59 (37%)
		Amino_oxidase	49..556	CDD:279874	119/529 (22%)
KDM1B	XP_016865929.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149528
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2622
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.870