Protein Alignment p and pink

DIOPT Version :10

• Sequence 1: NP_649810.1
• Gene: p / 41025
• FlyBaseID: FBgn0086679
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: XP_003436332.1
• Gene: pink / 11175731
• VectorBaseID: AGAMI1_000266
• Length: 891
• Species: Anopheles gambiae
• Alignment Length: 962
• Identity: 284/962 - (29%)
• Similarity: 428/962 - (44%)
• Gaps: 224/962 - (23%)

  Fly     5 YCLTNFIDFSLSLSLPLKHHNRIKYTCFDISDSYIIFGASSGSLYLFNR-NGKFLLLIPNKHGAI 68
            |.|.:..:.|..::.|.::::|||:||||.|..|.:|||:||||||::| ...||.:.|::.|.|
Mosquito     8 YALRDRAELSAFVNQPFRNNSRIKFTCFDCSPKYFVFGANSGSLYLYDRITTSFLAIFPSQLGTI 72

  Fly    69 TSLSISANSKYVAFATQRSLICVYAVNLSAQATPQVIFTHLDQSVQ-------------VTCIHW 120
            ..:|||.|.|.:|...|...|.| .:.|......:::.|.|..|..             ||...|
Mosquito    73 GKVSISHNEKQIAIGNQTGSIGV-LLELEPPHVKEILSTELAPSTDGEGQPIDLGGPAFVTSFCW 136

  Fly   121 TQDEKQFYYGDSRGQVSLVLLSSFIGHSLLFNMTVHPLLYLDSPIVQIDDFEYLLLVSNCTKCIL 185
            |:|:::.|.|||||.|||:..|.|:|.::| |:::||:|.|::.|||||.::.|||||..:||:|
Mosquito   137 TEDDRELYCGDSRGIVSLIQFSLFMGRNIL-NISLHPVLLLENRIVQIDRYKDLLLVSTLSKCVL 200

  Fly   186 CNTEYEDYKQIGNRPRDGAFGACFFVSPQESL--------QPS-----------RIYCARPGSRV 231
            |||..|::||||||||||.:||.|.::...::        .||           ||:|:|||||:
Mosquito   201 CNTAREEFKQIGNRPRDGQYGASFVIAHPNTIASATTTTTTPSPPLMIVDEEDVRIFCSRPGSRL 265

  Fly   232 WEVDFEGEVIQTHQFKTALATAPA----RIQRPGSGTDELD---------ANAELLDYQPQNLQF 283
            ||.|.||.||:|||||.|.|.|.|    |.:|......:|.         |..|..|.....:.|
Mosquito   266 WEADLEGNVIRTHQFKQAAAAAAAVAASRRRRSQQQQQQLQCLQESELATAPTEAPDGTLMVVPF 330

  Fly   284 AKVQRLNDDFLLAFTELGLYIFDIRRSAVVLWSNQFERIADCRSSGSEIFVFTQSGALYSVQLQT 348
            ..:..:....||......|.|.|...|.:||.:::|..|.........|::.|....::.|:::
Mosquito   331 QVLYSIRRQLLLVHDRCQLLIIDPLHSKIVLRTDEFTDITHVAVVDEWIYLLTGENRVFQVRVE- 394

  Fly   349 LQSHAVSLIQQSKLLPCANLLRQHVRYFADKAREDYELKQLNPLKQLLIERQEYELLNDISVIFD 413
                                                            |:..|
Mosquito   395 ------------------------------------------------IQGDE------------ 399

  Fly   414 AITQCTGSALDTHSSGGSSATTERSLSGGSSSRAPPKGVYVLENAFCDN----------LKQPL- 467
                      |...:.|  ...|..|    .||...:|||:|::...:|          .:.||
Mosquito   400 ----------DPFPTPG--MVDEPCL----ESRKQKQGVYILDSMLNNNNNNNGKQMNGKESPLL 448

  Fly   468 --KTGHFKDALLTVT-GKFGKNIIKYKFNIFAEEQQQLVRELIPASERSL-------PFKD---- 518
              .....|:||::|. ||:|:| ||..|..:.::|||......|...::|       |.:.
Mosquito   449 LSTEATIKEALVSVVRGKYGRN-IKQMFMGYEQQQQQRTPSGAPERPKTLNLTKIYEPSRSNAFA 512

  Fly   519 ------------IKARYES-GSEDQEEEIVRRCKKPA-------------PQVP----------- 546
                        |:|..|. ..:|..||:|:.....|             .|.|
Mosquito   513 NGNGHALLAEFGIEAEVEDLECDDMMEELVQTRTGQALLGTAMPNGAGTGKQQPGKKKFSTSLLD 577

  Fly   547 --HISPEEKTLYNLYLIAKSAKFSRTQCVDRYRAVFDEYAAGELVNLLEKLAQVMVEHGDTPDQA 609
              ..|.::.|:.|||||.:|:..|.....|||..:||||....:|.||.|| :.::|..:.|: |
Mosquito   578 GYETSEDDATVRNLYLIFRSSIISNLNFADRYAKIFDEYDTETIVRLLRKL-ETLMEENEEPN-A 640

  Fly   610 QRNCYEMYFDYLDPEMIWEVDDATRDHIAAGFVLLNTSQNAE------IVKCEHCSFPLRFDTSC 668
            :..|..:||.||.||::||:|..:|..|..||::.||:..|:      :..|..|.:.|....||
Mosquito   641 RLKCMRIYFHYLKPELLWEIDADSRQFIKDGFIVCNTTDGADRARLERLAHCAACGYYLEATASC 705

  Fly   669 QYHELGAVLLRYFWSRGEQLKCFDVVQSVPALLDVLAKFYLAEQNLTKVVAIVLNYGLPELLADV 733
            .|.|:|..||:|:|||.|..:||.:|:.||.|...:.::|:.::...|||..|.|....|||...
Mosquito   706 HYREIGTSLLQYYWSRKEYDECFAMVKRVPYLWRTITRYYIQDRREDKVVQCVWNLADSELLERA 770

  Fly   734 GKQL--SVSAWGRCFEQFVELQRGGRLVCANCECISG--VEQEQL-----------GRH------ 777
            ..:|  .:..|.:.||..:...:...::|.:|:..:|  :|..|.           |.|
Mosquito   771 AGELPFELDHWRQLFELAIAYHQRHEMICLSCDKPTGGRLEDNQRDNRSAAKANGGGDHRAAGST 835

  Fly   778 ----FFYNWNCFLNIALDHM-SAGDTLALIFKWSSYIPNDAIDREFYSRCLL 824
                .|..||..|.:||.|: |..:.|.|:.:::..||..||...||.||||
Mosquito   836 EAESQFRQWNYLLGVALAHIRSPTELLCLVRRYADNIPRGAIAPSFYIRCLL 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p	NP_649810.1	WD40	<20..148	CDD:441893	55/141 (39%)
		WD40 repeat	25..63	CDD:293791	21/38 (55%)
		WD40 repeat	68..107	CDD:293791	11/38 (29%)
		WD40 repeat	116..154	CDD:293791	18/37 (49%)
		WD40 repeat	161..196	CDD:293791	19/34 (56%)
		WD40 repeat	204..245	CDD:293791	21/59 (36%)
pink	XP_003436332.1	None