DRSC/TRiP Functional Genomics Resources

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Protein Alignment p and Tecpr2

DIOPT Version :10

Sequence 1:NP_649810.1 Gene:p / 41025 FlyBaseID:FBgn0086679 Length:826 Species:Drosophila melanogaster
Sequence 2:NP_001074526.1 Gene:Tecpr2 / 104859 MGIID:2144865 Length:1423 Species:Mus musculus


Alignment Length:560 Identity:122/560 - (21%)
Similarity:206/560 - (36%) Gaps:138/560 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 TCFDISDSYIIFGASSGSLYLF----NRNGKFLLLIPNKHGAITSLSI----SANSKYVAFATQR 86
            |..|.:..||..|:|.|.|||:    |:..|:     |..|.:.|:::    |.....||..|..
Mouse    39 TALDTNGDYIAVGSSIGMLYLYCRHLNQMKKY-----NVDGKMESITVVKLLSCFDDLVAAGTAS 98

  Fly    87 SLICVYAVNLSAQATPQ------VIFTHLDQSVQVTCIHWTQDEKQFYYGDSRGQVSLVLLSSFI 145
            ..:.|:.:..|.....:      |...|   ...:|.:.|:.:..:.:.||.:|::  |..|..:
Mouse    99 GRVAVFQLVSSLPGRNKQLRRFDVTGVH---KTSITALAWSPNGMKLFSGDDKGKI--VYSSLDL 158

  Fly   146 GHSLLFNMTVHPLLYLDSPIVQIDDFEYLLLVSNCTKCILCNTEYEDYKQIGNRPR--DGAFGAC 208
            ...|   .:.|.:|...|.|||:|..:.:||||...:.:|..||.:..||||::||  .|.||||
Mouse   159 DQGL---CSSHLVLEEPSSIVQLDYSQKVLLVSTLQRSLLFYTEEKAVKQIGSQPRKSTGKFGAC 220

  Fly   209 FF--VSPQESLQPSRIYCARPGSRVWEVDFEGEVIQTHQFKTALATAPARIQRPGSGTD-ELDAN 270
            |.  :..|..|   .:|.||||.|:|:.|..|.|..|:..|...|         |..|. ||...
Mouse   221 FIPGLCKQSDL---TLYAARPGLRLWKADVHGTVQATYILKDVFA---------GGVTPFELYPR 273

  Fly   271 AELLD----YQPQNLQFAKVQRLNDDFLLAFTELGLYIFDIRRSAVVLWSNQFERIADCRSSGSE 331
            .|..|    ..|:...........:.::|::.|..:|:.|....|.|........|.....:.:|
Mouse   274 LEPSDGGSCISPEKHLGLVSCFFREGWVLSWNEYSIYLLDTVNQATVAGLEGLGDIVSVSCTENE 338

  Fly   332 IFVFTQSGALYSVQLQTLQSHAVSLIQQS-KLLPCANLLR-QHVRYFADKAREDYELKQLNPLKQ 394
            ||..  .|....:::.:......|:::.. ::..|:..:. ||:.........:..|:..:....
Mouse   339 IFFL--KGDRNIIRISSRPEGIASIVRDGLEMTRCSEQVHGQHLEKSLGATVCETRLRGSSVASS 401

  Fly   395 LLIERQEYELLNDISVIFDAITQCTGSALDTHSSG------GSSATTERSLSGGSSSRAPPKGVY 453
            :..|::.                 ..|:|::..||      |..|.:|...||..||:       
Mouse   402 VASEQRS-----------------RSSSLNSTDSGSGLLLPGLQAASELGQSGQPSSQ------- 442

  Fly   454 VLENAFCDNLKQPLKTGHFKDALLTVTGKFGKNIIKYKFNIFAEE--QQQLVRELIPASERSLPF 516
                                                 :|::.:.|  .|:|:.:.|...:|..  
Mouse   443 -------------------------------------RFSVISSEDFDQELIVKPIKVKKRRR-- 468

  Fly   517 KDIKARYESGSEDQEEEIVRRC-----KKPAPQVPHISPE 551
               |.:.|.||:.       .|     ..|..::|..||:
Mouse   469 ---KRKTEGGSKS-------TCPSSLESTPCSELPADSPQ 498

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pNP_649810.1 WD40 <20..148 CDD:441893 30/131 (23%)
WD40 repeat 25..63 CDD:293791 12/36 (33%)
WD40 repeat 68..107 CDD:293791 8/48 (17%)
WD40 repeat 116..154 CDD:293791 8/37 (22%)
WD40 repeat 161..196 CDD:293791 13/34 (38%)
WD40 repeat 204..245 CDD:293791 18/42 (43%)
Tecpr2NP_001074526.1 WD40 repeat 37..73 CDD:293791 13/38 (34%)
WD40 repeat 79..121 CDD:293791 6/41 (15%)
ANAPC4_WD40 90..>151 CDD:403945 12/63 (19%)
WD40 repeat 130..168 CDD:293791 9/42 (21%)
WD40 repeat 175..197 CDD:293791 9/21 (43%)
Hyd_WA 959..986 CDD:461921
Hyd_WA 1008..1039 CDD:461921
Tectonin 1191..1385 CDD:465992
Blue background indicates that the domain is not in the aligned region.

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