DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhod and dpyd-1

DIOPT Version :9

Sequence 1:	NP_477224.1	Gene:	Dhod / 41022	FlyBaseID:	FBgn0000447	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_508927.2	Gene:	dpyd-1 / 180818	WormBaseID:	WBGene00016103	Length:	1059	Species:	Caenorhabditis elegans

Alignment Length:	348	Identity:	76/348 - (21%)
Similarity:	140/348 - (40%)	Gaps:	84/348 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 DDQNLHTSFFGRMLSNPIGIAA------------GFDKNAEAVDGLQDLGFGFIEVGT------- 127
            |:.::.....|....||.|:|:            .|::           |:|||...|
Worm   543 DEVDISVDMCGVKFENPFGLASAPPTTSGPMCRRAFEQ-----------GWGFILTKTYGLDKDL 596

  Fly   128 VTPAAQEGNPKPRVFRLTEDKAIINRYGFNSDGHQAV-----------LQRLRLLRKKENFNGVV 181
            ||      |..||:.|.:....:   ||.|......:           ||.:|.|::......|:
Worm   597 VT------NVSPRIVRGSTSGPL---YGPNQGSFMNIELISEKSCEYWLQCIRELKRDHPTKIVI 652

  Fly   182 -GVNLGRNKTTMSPIADYVQ-GVRVFGPVADYLVINVSSPNTKGLRDM-----QSKEKLRELLEQ 239
             .:....||      ||::: ..:.....||.|.:|:|.|:..|.:.|     ||.|.::|:...
Worm   653 ASIMCVYNK------ADWIELATKSEEAGADILELNLSCPHGMGEKGMGLACGQSPEIVKEICRW 711

  Fly   240 VNDTKSSLDKNKNVPILLKLSPDLSLDDMKDIVWVIKRKKSRVDGLIVSNTTVSRENIEKNKLA- 303
            |...       ..:|...|::|:::  |:::|...  .:.....|:..:||..|..:::.:..|
Worm   712 VRAC-------VKIPFFPKMTPNIT--DVREIARA--ARDGGASGVTATNTVSSLMHMKADGNAW 765

  Fly   304 ------EET--GGLSGPPLKARSTEMIAQMYQLTDGKIPIIGVGGVASGYDAYEKIEAGASYVQI 360
                  :.|  ||:||..::..:.:.::.:....|| .||:..||:.|.......:.||||.:|:
Worm   766 PAIGSTKRTTYGGMSGSAIRPIAMKAVSSIANELDG-FPIMATGGIESAETGLGFLMAGASVLQV 829

  Fly   361 YTALVYEGPALVEDIKAELSALI 383
            .:|:..:...:|:|....|.||:
Worm   830 CSAVQNQDFTVVDDYCTGLKALL 852

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhod	NP_477224.1	PRK05286	45..387	CDD:235388	76/348 (22%)
Dhod	NP_477224.1	DHOD_2_like	51..379	CDD:240089	73/342 (21%)
dpyd-1	NP_508927.2	PRK11749	69..523	CDD:236967
		Fer4_20	71..183	CDD:291363
		NAD_binding_8	206..>251	CDD:290186
		PRK08318	546..1019	CDD:236237	75/345 (22%)
		DHPD_FMN	546..848	CDD:239244	72/339 (21%)
		Fer4_9	964..1009	CDD:289930
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0167
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810