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Protein Alignment Dhod and DPYD

DIOPT Version :9

Sequence 1:	NP_477224.1	Gene:	Dhod / 41022	FlyBaseID:	FBgn0000447	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_000101.2	Gene:	DPYD / 1806	HGNCID:	3012	Length:	1025	Species:	Homo sapiens

Alignment Length:	332	Identity:	71/332 - (21%)
Similarity:	133/332 - (40%)	Gaps:	72/332 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 GRMLSNPIGIAAGFDKNAEA-VDGLQDLGFGF-------IEVGTVTPAAQEGNPKPRVFRLTEDK 148
            |....||.|:|:.....:.: :....:.|:||       ::...||      |..||:.|.|...
Human   539 GLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVT------NVSPRIIRGTTSG 597

  Fly   149 AIINRYGFNSDGHQAVLQRLRLLRKK-----------------ENFNGVVGVNLGRNKTTMSPIA 196
            .:   ||   .|..:.| .:.|:.:|                 :|. .:..:....||...:.:|
Human   598 PM---YG---PGQSSFL-NIELISEKTAAYWCQSVTELKADFPDNI-VIASIMCSYNKNDWTELA 654

  Fly   197 DYVQGVRVFGPVADYLVINVSSPNTKGLRDM-----QSKEKLRELLEQVNDTKSSLDKNKNVPIL 256
            ...:     ...||.|.:|:|.|:..|.|.|     |..|.:|.:...|...       ..:|..
Human   655 KKSE-----DSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQA-------VQIPFF 707

  Fly   257 LKLSPDLSLDDMKDIVWVIK-RKKSRVDGLIVSNTTVSRENIEKN-------KLAEET--GGLSG 311
            .||:|:::     |||.:.: .|:...:|:..:||......::.:       .:|:.|  ||:||
Human   708 AKLTPNVT-----DIVSIARAAKEGGANGVTATNTVSGLMGLKSDGTPWPAVGIAKRTTYGGVSG 767

  Fly   312 PPLKARSTEMIAQMYQLTDGKIPIIGVGGVASGYDAYEKIEAGASYVQIYTALVYEGPALVEDIK 376
            ..::..:...:..:.:...| .||:..||:.|.....:.:.:|||.:|:.:|:..:...::||..
Human   768 TAIRPIALRAVTSIARALPG-FPILATGGIDSAESGLQFLHSGASVLQVCSAIQNQDFTVIEDYC 831

  Fly   377 AELSALI 383
            ..|.||:
Human   832 TGLKALL 838

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.