Protein Alignment Mkk4 and PBS2

DIOPT Version :9

• Sequence 1: NP_001163551.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_012407.2
• Gene: PBS2 / 853313
• SGDID: S000003664
• Length: 668
• Species: Saccharomyces cerevisiae
• Alignment Length: 430
• Identity: 161/430 - (37%)
• Similarity: 236/430 - (54%)
• Gaps: 43/430 - (10%)

  Fly     2 AERPKNLFATGSSRSRNPPDQLSLNNLSIRHPPSSTSSTSSGSTSSGSSSSSQHNHVTRCFGAQQ 66
            |::|:. ||...|..:: .:.|| |:..:....|:..|..:|..|:.:|||::..|.|  .|.
Yeast   239 AQQPQQ-FAPSPSNKKH-IETLS-NSKVVEGKRSNPGSLINGVQSTSTSSSTEGPHDT--VGT-- 296

  Fly    67 PQQTPPVASSQVPPVPAASSSSAADRHRERIRQQACGKLQFG------------EGGANTHTFTS 119
               ||...:|.......:|.......:..:......|.|.|.            ..|:::. .|.
Yeast   297 ---TPRTGNSNNSSNSGSSGGGGLFANFSKYVDIKSGSLNFAGKLSLSSKGIDFSNGSSSR-ITL 357

  Fly   120 DDLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLEVVMKSNECIYIVQF 184
            |:||...|:|.|.:|.|:|:..|..:.:||.|.:|..:||.:.:|:||:|||:.|.|. .|||.|
Yeast   358 DELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELEVLHKCNS-PYIVDF 421

  Fly   185 YGALFKEGDCWICMELMD-TSLDKFYKYIYEKQQR--HIPESILAKITVATVNALNYLKEELKII 246
            |||.|.||..::|||.|| .||||    ||::...  .|.|..||.|..|.::.|..|||:..||
Yeast   422 YGAFFIEGAVYMCMEYMDGGSLDK----IYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNII 482

  Fly   247 HRDVKPSNILLH-RRGDIKLCDFGISGQLVDSIAKTKDAGCRPYMAPERI---DPERAKGYDVRS 307
            ||||||:|||.. .:|.:||||||:||.||.|:||| :.||:.|||||||   :|:||. |.|:|
Yeast   483 HRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKT-NIGCQSYMAPERIKSLNPDRAT-YTVQS 545

  Fly   308 DVWSLGITLMEVATGNFPY--RKWDSVFEQLCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIK 370
            |:||||::::|:|.|.:||  ..:|::|.||..:|.|.||||.:.    :||.:..|||:.||.|
Yeast   546 DIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSD----KFSSDAQDFVSLCLQK 606

  Fly   371 KESDRPKYSRLLEMPFIRRGETSHTDVAVYVADILESMEK 410
            ....||.|:.|.|.|::.:.......::.|:.:.||...|
Yeast   607 IPERRPTYAALTEHPWLVKYRNQDVHMSEYITERLERRNK 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_001163551.1	PKc_MKK4	115..405	CDD:270790	132/298 (44%)
		S_TKc	123..387	CDD:214567	128/272 (47%)
PBS2	NP_012407.2	PKc_PBS2_like	358..644	CDD:132953	133/296 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	255	1.000	Inparanoid score	I647
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48013
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2221
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.090