Protein Alignment Mkk4 and STE7

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_010122.1
• Gene: STE7 / 851396
• SGDID: S000002318
• Length: 515
• Species: Saccharomyces cerevisiae
• Alignment Length: 404
• Identity: 131/404 - (32%)
• Similarity: 193/404 - (47%)
• Gaps: 72/404 - (17%)

  Fly    13 SSRSRNPP---DQLSLNNLSIRHPPSSTSSTSS---GSTSSGSSSSSQHNHVTRCFGAQQPQQTP 71
            ||.|.:.|   |..| ||..:  .||||:||.|   |.::..:...::|
Yeast   110 SSSSLSTPCIIDAYS-NNFGL--SPSSTNSTPSTIQGLSNIATPVENEH---------------- 155

  Fly    72 PVASSQVPPVPAASSSSAADRHRERIRQQACGKLQFGEGGANTHTFTSDDLEDEGEIGRGAFGAV 136
               |..:||:..:.|.:|||. ::.:           .|.:|.:.....||...|:||.|..|.|
Yeast   156 ---SISLPPLEESLSPAAADL-KDTL-----------SGTSNGNYIQLQDLVQLGKIGAGNSGTV 205

  Fly   137 NKMTFKKLDKVMAVKRI-----RSTVDEKEQKQLLMDLEVVMKSNECIYIVQFYGALFKE---GD 193
            .|.......|::|.|.|     .||:    ..||:.:|.:|........|:.||||.:.:   .:
Yeast   206 VKALHVPDSKIVAKKTIPVEQNNSTI----INQLVRELSIVKNVKPHENIITFYGAYYNQHINNE 266

  Fly   194 CWICMELMDT-SLDKF---YKYIYEK-----QQRHIPESILAKITVATVNALNYLKEELKIIHRD 249
            ..|.||..|. ||||.   ||...::     ::....|..::||....:|.|::|..:.||||||
Yeast   267 IIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRD 331

  Fly   250 VKPSNILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPYMAPERIDPERAKGYDVRSDVWSLGI 314
            :||||:|::.:|.|||||||:|.:|::|||.| ..|...||:||||   :...|.::.||||||:
Yeast   332 IKPSNVLINSKGQIKLCDFGVSKKLINSIADT-FVGTSTYMSPERI---QGNVYSIKGDVWSLGL 392

  Fly   315 TLMEVATGNFPYRKW----DSVFEQLCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIKKESDR 375
            .::|:.||.||....    |.:.:.|.::|....|||   .....:|||..||||.|.||.|.:|
Yeast   393 MIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRL---PKDRIYSKEMTDFVNRCCIKNERER 454

  Fly   376 PKYSRLLEMPFIRR 389
            .....||....|.:
Yeast   455 SSIHELLHHDLIMK 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	105/296 (35%)
STE7	NP_010122.1	PKc_Byr1_like	185..482	CDD:270792	105/295 (36%)