Protein Alignment Mkk4 and Stk3

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_038935793.1
• Gene: Stk3 / 65189
• RGDID: 68412
• Length: 532
• Species: Rattus norvegicus
• Alignment Length: 295
• Identity: 97/295 - (32%)
• Similarity: 159/295 - (53%)
• Gaps: 31/295 - (10%)

  Fly   120 DDLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLEVVMKSNECIYIVQF 184
            |.||   ::|.|::|:|.|...|:..:|:|:|::..   |.:.::::.::. :|:..:..|:|::
  Rat    28 DVLE---KLGEGSYGSVFKAIHKESGQVVAIKQVPV---ESDLQEIIKEIS-IMQQCDSPYVVKY 85

  Fly   185 YGALFKEGDCWICMELMDTSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKEELKIIHRD 249
            ||:.||..|.||.||.....   ....|...:.:.:.|..:|.|..:|:..|.|| ..::.||||
  Rat    86 YGSYFKNTDLWIVMEYCGAG---SVSDIIRLRNKTLTEDEIATILKSTLKGLEYL-HFMRKIHRD 146

  Fly   250 VKPSNILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPY-MAPERIDPERAKGYDVRSDVWSLG 313
            :|..||||:..|..||.|||::|||.|::||.......|: ||||.|   :..||:..:|:||||
  Rat   147 IKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI---QEIGYNCVADIWSLG 208

  Fly   314 ITLMEVATGNFPY---RKWDSVFEQLCQVVQGEPPRLLTSYNGME-FSKEFVDFVNTCLIKKESD 374
            ||.:|:|.|..||   ....::|     ::...||   .::...| :|.:|.|||..||:|....
  Rat   209 ITSIEMAEGKPPYADIHPMRAIF-----MIPTNPP---PTFRKPELWSDDFTDFVKKCLVKSPEQ 265

  Fly   375 RPKYSRLLEMPFIRRGETSHTDVAVYVADILESME 409
            |...::||:.|||:..:    .|::....|.|.||
  Rat   266 RATATQLLQHPFIKNAK----PVSILRELITEGME 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	93/289 (32%)
Stk3	XP_038935793.1	STKc_MST1_2	23..278	CDD:132943	90/271 (33%)
		Mst1_SARAH	481..525	CDD:463314