Protein Alignment Mkk4 and Map2k2

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_063120246.1
• Gene: Map2k2 / 58960
• RGDID: 61888
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 364
• Identity: 122/364 - (33%)
• Similarity: 180/364 - (49%)
• Gaps: 80/364 - (21%)

  Fly    71 PPVASSQVPPVPAASSSSAAD------------RHRERIRQQACGKLQFGEGGANTHTFTSDDLE 123
            |.:|....|....||.:...|            :.|:|:......|.:.||       ...||.|
  Rat    16 PTIAEGPSPTSEGASEAHLVDLQKKLEELDLDEQQRKRLEAFLTQKAKVGE-------LKDDDFE 73

  Fly   124 DEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLEVVMKSNECIYIVQFYGAL 188
            ...|:|.|..|.|.|...:....:||.|.|...:....:.|::.:|:|:.:.|. .|||.||||.
  Rat    74 RISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNS-PYIVGFYGAF 137

  Fly   189 FKEGDCWICMELMD-TSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKEELKIIHRDVKP 252
            :.:|:..||||.|| .|||:..     |:.:.|||.||.|:::|.:..|.||:|:.:|:||||||
  Rat   138 YSDGEISICMEHMDGGSLDQVL-----KEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKP 197

  Fly   253 SNILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPYMAPERIDPERAKGYDVRSDVWSLGITLM 317
            ||||::.||:|||||||:||||:||:|.: ..|.|.||:|||:   :...|.|:||:||:|::|:
  Rat   198 SNILVNSRGEIKLCDFGVSGQLIDSMANS-FVGTRSYMSPERL---QGTHYSVQSDIWSMGLSLV 258

  Fly   318 EVATGNFPYRKWD----------------------------------------------SVFEQL 336
            |:|.|.:|....|                                              ::||.|
  Rat   259 ELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPISVGHGMDSRPAMAIFELL 323

  Fly   337 CQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIKKESDR 375
            ..:|...||:|.:..    ||.:|.:|||.||||..::|
  Rat   324 DYIVNEPPPKLPSGV----FSSDFQEFVNKCLIKNPAER 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	111/308 (36%)
Map2k2	XP_063120246.1	None