Protein Alignment Mkk4 and map2k2a

DIOPT Version :9

• Sequence 1: NP_001163551.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001032468.2
• Gene: map2k2a / 563181
• ZFINID: ZDB-GENE-041027-1
• Length: 397
• Species: Danio rerio
• Alignment Length: 396
• Identity: 133/396 - (33%)
• Similarity: 197/396 - (49%)
• Gaps: 85/396 - (21%)

  Fly    67 PQQTP------PVASSQVPPVPAASSSSAA------------DRHRERIRQQACGKLQFGEGGAN 113
            |::.|      |....|...:.||:.::..            ::.|:|:......|.|.||
Zfish     3 PKRRPVPLIITPTGEGQSTNIDAAAEANLEALQRKLGELDLDEQQRKRLEAFLTQKAQVGE---- 63

  Fly   114 THTFTSDDLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLEVVMKSNEC 178
               ...:|.|...|:|.|..|.|:|:..|....|||.|.|...:....:.|::.:|:|:.:.|.
Zfish    64 ---LKDEDFEPICELGAGNGGVVHKVRHKPSRLVMARKLIHLEIKPAIRNQIIRELQVLHECNS- 124

  Fly   179 IYIVQFYGALFKEGDCWICMELMD-TSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKEE 242
            .|||.||||.:.:|:..||||.|| .|||:..     |:.|.|||.||.|:::|.:..|.||:|:
Zfish   125 PYIVGFYGAFYSDGEISICMEHMDGGSLDQVL-----KEARRIPEEILGKVSIAVLRGLAYLREK 184

  Fly   243 LKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPYMAPERIDPERAKGYDVRS 307
            .:|:||||||||||::.||:|||||||:||||:||:|.: ..|.|.||:|||:   :...|.|:|
Zfish   185 HQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANS-FVGTRSYMSPERL---QGTHYSVQS 245

  Fly   308 DVWSLGITLMEVATGNFPYRKWD------------------------------------------ 330
            ||||:|::|:|:|.|.:|....|
Zfish   246 DVWSMGLSLVELAIGRYPIPPPDAKELEAIFGRPVLDAGGAEGHSMSPRPRPPGRPVSGHGMDSR 310

  Fly   331 ---SVFEQLCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIKKESDRPKYSRLLEMPFIRRGET 392
               ::||.|..:|...||:|   .:|: |:.:|.:||..||||..:||.....|:...||:|.|.
Zfish   311 PAMAIFELLDYIVNEPPPKL---PHGV-FTTDFEEFVTKCLIKNPADRADLKMLMGHTFIKRAEV 371

  Fly   393 SHTDVA 398
            ...|.|
Zfish   372 EEVDFA 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_001163551.1	PKc_MKK4	115..405	CDD:270790	121/330 (37%)
		S_TKc	123..387	CDD:214567	114/309 (37%)
map2k2a	NP_001032468.2	PKc_MEK2	63..393	CDD:132980	122/336 (36%)
		S_TKc	69..366	CDD:214567	114/310 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D688282at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2221
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.950