Protein Alignment Mkk4 and stk25a

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_005165982.1
• Gene: stk25a / 449653
• ZFINID: ZDB-GENE-041010-92
• Length: 424
• Species: Danio rerio
• Alignment Length: 325
• Identity: 98/325 - (30%)
• Similarity: 157/325 - (48%)
• Gaps: 53/325 - (16%)

  Fly    93 HRERIRQQACGKLQFGEGGANTHTFTSDDLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTV 157
            |.:.||.|            |:.....:.......||:|:||.|.|....:..:|:|:|    .:
Zfish     3 HLQNIRNQ------------NSRLNPEEYFTKLERIGKGSFGEVYKGINNRTKEVVAIK----II 51

  Fly   158 DEKEQKQLLMDLE---VVMKSNECIYIVQFYGALFKEGDCWICMELM--DTSLDKFYKYIYEKQQ 217
            |.:|.:..:.|::   .|:...:..|:.::||:.......||.||.:  .::||.
Zfish    52 DLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLTGSKLWIIMEYLGGGSALDL---------- 106

  Fly   218 RHIPESILAKITVATV-----NALNYLKEELKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDS 277
              :....|.::.:||:     ..|:||..|.| ||||:|.:|:||...|::||.|||::|||.|:
Zfish   107 --LRPGTLEEVYIATILREILKGLDYLHSERK-IHRDIKAANVLLSEHGEVKLADFGVAGQLTDT 168

  Fly   278 -IAKTKDAGCRPYMAPERIDPERAKGYDVRSDVWSLGITLMEVATGNFPYRKWDSVFEQLCQVVQ 341
             |.:....|...:||||.|   :...||.::|:||||||.:|:|.|..|..:...: ..|..:.:
Zfish   169 QIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNAELHPM-RVLFLIPK 229

  Fly   342 GEPPRLLTSYNGMEFSKEFVDFVNTCLIKKESDRPKYSRLLEMPFIRRGETSHTDVAVYVADILE 406
            ..||.|..||     ||.|.|||..||.|:...||....||:..||    |.:|....|::::::
Zfish   230 NNPPTLEGSY-----SKAFKDFVEACLNKEPRFRPTAKELLKHKFI----TRYTKKTSYLSELID 285

  Fly   407  406
            Zfish   286  285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	93/300 (31%)
stk25a	XP_005165982.1	STKc_MST3_like	20..291	CDD:270786	93/296 (31%)