Protein Alignment Mkk4 and Mekk1

DIOPT Version :9

• Sequence 1: NP_001163551.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Alignment Length: 465
• Identity: 114/465 - (24%)
• Similarity: 183/465 - (39%)
• Gaps: 126/465 - (27%)

  Fly     4 RPKNLFATGSSRSRNP---------------PDQLSLNNLSIRHPPSSTSSTSSGSTSSGSSSSS 53
            |.:...:..:||||.|               |...|.....:.||..|.....||::.|...||
  Fly  1129 RTRKTSSPATSRSRTPTRTPMSAGMVLNPNTPPLQSPPYNKLLHPQFSLKEDVSGTSYSPVDSS- 1192

  Fly    54 QHNHVTRCFGAQQPQQTPPVASS---------QVPPVPAASSSSAADR-----HRERIRQQACGK 104
              ::|          .||...|:         |.||.||:...|:.:.     .:||:| .|..:
  Fly  1193 --DYV----------DTPCQRSANGELRLLVPQTPPTPASPGKSSLESTPLALRQERVR-DAVNR 1244

  Fly   105 LQFGEGGANTHTFTSDDLED--------------------------------EG-EIGRGAFGAV 136
            |..             ||||                                .| :||:|.||.|
  Fly  1245 LDM-------------DLEDGLRERRLIGQVKSLNSSDKVHIRARSVHFRWHRGIKIGQGRFGKV 1296

  Fly   137 NKMTFKKLDKVMAVKRIRSTVDE----KEQKQLLMDLEVVMKSNECIYIVQFYGALFKEGDCWIC 197
            .........::||:|.|.....|    |...:.|..||.:...|    :|::||......:..|.
  Fly  1297 YTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKN----LVRYYGIEVHREELLIF 1357

  Fly   198 MEL-MDTSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKEELKIIHRDVKPSNI-LLHRR 260
            ||| .:.:|:...:.     ..::||::..:.|...::.::.|.:. .|:|||:|.:|| |:...
  Fly  1358 MELCSEGTLESLVEL-----TGNLPEALTRRFTAQLLSGVSELHKH-GIVHRDIKTANIFLVDGS 1416

  Fly   261 GDIKLCDFG----------ISGQLVDSIAKTKDAGCRPYMAPERIDPERAKGYDVRSDVWSLGIT 315
            ..:||.|||          :.|:|...:      |.:.|||||......:.|:...:|:||:|..
  Fly  1417 NSLKLGDFGSAVKIQAHTTVPGELQGYV------GTQAYMAPEVFTKTNSDGHGRAADIWSVGCV 1475

  Fly   316 LMEVATGNFPYRKWDSVFEQLCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIKKESDRPKYSR 380
            ::|:|:|..|:.::||.|:.:.:|..||.|:...|     .|:|..||::.||......|.....
  Fly  1476 VVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPES-----LSQEGHDFIDHCLQHDPKRRLTAVE 1535

  Fly   381 LLEMPFIRRG 390
            |||..|.:.|
  Fly  1536 LLEHNFCKYG 1545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_001163551.1	PKc_MKK4	115..405	CDD:270790	83/325 (26%)
		S_TKc	123..387	CDD:214567	79/312 (25%)
Mekk1	NP_732373.1	STKc_MEKK4	1281..1542	CDD:270796	77/281 (27%)
		S_TKc	1282..1541	CDD:214567	77/279 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447166
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930