Protein Alignment Mkk4 and hpo

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_611427.1
• Gene: hpo / 37247
• FlyBaseID: FBgn0261456
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 94/267 - (35%)
• Similarity: 150/267 - (56%)
• Gaps: 18/267 - (6%)

  Fly   127 EIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLEVVMKSNECIYIVQFYGALFKE 191
            ::|.|::|:|.|...|:...::|:|.:..   |.:..:::.::. :|:..:..|:|::||:.||:
  Fly    47 KLGEGSYGSVYKAVHKESSSIVAIKLVPV---ESDLHEIIKEIS-IMQQCDSPYVVRYYGSYFKQ 107

  Fly   192 GDCWICMELMDTSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKEELKIIHRDVKPSNIL 256
            .|.|||||.....   ....|...:::.:.|..:|.|...|:..|.||....| ||||:|.:|||
  Fly   108 YDLWICMEYCGAG---SVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRK-IHRDIKAANIL 168

  Fly   257 LHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPY-MAPERIDPERAKGYDVRSDVWSLGITLMEVA 320
            |:..|..||.|||::|||.|::||.......|: ||||.|:   ..|||..:|:||||||.:|:|
  Fly   169 LNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIE---EIGYDCVADIWSLGITALEMA 230

  Fly   321 TGNFPYRKWDSVFEQLCQVVQGEPPRLLTSYNGME-FSKEFVDFVNTCLIKKESDRPKYSRLLEM 384
            .|..||.:...: ..:..:.|..||    |:...: :|.||:|||:.||:|:..||...:.|||.
  Fly   231 EGKPPYGEIHPM-RAIFMIPQKPPP----SFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEH 290

  Fly   385 PFIRRGE 391
            .|||..:
  Fly   291 EFIRNAK 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	94/267 (35%)
hpo	NP_611427.1	STKc_MST1_2	38..293	CDD:132943	91/261 (35%)
		SARAH_Hpo	606..661	CDD:439183