Protein Alignment Mkk4 and Map2k7

DIOPT Version :9

• Sequence 1: NP_001163551.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_006248831.1
• Gene: Map2k7 / 363855
• RGDID: 1560043
• Length: 468
• Species: Rattus norvegicus
• Alignment Length: 426
• Identity: 184/426 - (43%)
• Similarity: 241/426 - (56%)
• Gaps: 52/426 - (12%)

  Fly     3 ERPKNLFATGSSRSRNPPD----QLSLNNLSIRHPPSSTSSTSSGSTSSGSSSSSQHNHVTRCFG 63
            :||:.:.....|.:..|..    ||.|.|             ..||.|..|.||.||
  Rat    37 QRPRPIIVITLSPAPAPSQRAALQLPLAN-------------DGGSRSPSSESSPQH-------- 80

  Fly    64 AQQPQQTPPVASSQVPPVPA------ASSSSAADRHRERIRQQACGKLQFGEGGANTHTFTSDDL 122
                 .|||.....:..:|:      :..|...|:..:.|.:|. |.|..   |...:....:||
  Rat    81 -----PTPPSRPRHMLGLPSTLFTPRSMESIEIDQKLQEIMKQT-GYLTI---GGQRYQAEINDL 136

  Fly   123 EDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLEVVMKSNECIYIVQFYGA 187
            |:.||:|.|..|.|.||.|:|...::|||::|.:.:::|.|::||||:||:||::|.||||.:|.
  Rat   137 ENLGEMGSGTCGQVWKMRFRKTGHIIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGT 201

  Fly   188 LFKEGDCWICMELMDTSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKEELKIIHRDVKP 252
            .....|.:|.||||.|..:|..|    :.|..|||.||.|:|||.|.||.||||:..:|||||||
  Rat   202 FITNTDVFIAMELMGTCAEKLKK----RMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKP 262

  Fly   253 SNILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPYMAPERIDP--ERAKGYDVRSDVWSLGIT 315
            |||||..||.||||||||||:||||.|||:.|||..|||||||||  .....||:|:|||||||:
  Rat   263 SNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGIS 327

  Fly   316 LMEVATGNFPYRKWDSVFEQLCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIKKESDRPKYSR 380
            |:|:|||.|||:...:.||.|.:|:|.||| ||..:.|  ||.:|..||..||.|....||||::
  Rat   328 LVELATGQFPYKNCKTDFEVLTKVLQEEPP-LLPGHMG--FSGDFQSFVKDCLTKDHRKRPKYNK 389

  Fly   381 LLEMPFIRRGETSHTDVAVYVADIL---ESMEKDGI 413
            |||..||:..||...|||.:..|::   ||....|:
  Rat   390 LLEHSFIKHYETLEVDVASWFKDVMAKTESPRTSGV 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_001163551.1	PKc_MKK4	115..405	CDD:270790	154/291 (53%)
		S_TKc	123..387	CDD:214567	144/265 (54%)
Map2k7	XP_006248831.1	PKc_MKK7	120..416	CDD:270791	157/305 (51%)
		S_TKc	137..396	CDD:214567	144/265 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D470057at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920