Protein Alignment Mkk4 and Map2k3

DIOPT Version :9

• Sequence 1: NP_001163551.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001094144.1
• Gene: Map2k3 / 303200
• RGDID: 1306620
• Length: 347
• Species: Rattus norvegicus
• Alignment Length: 376
• Identity: 176/376 - (46%)
• Similarity: 237/376 - (63%)
• Gaps: 43/376 - (11%)

  Fly    33 PPSSTSSTSSGSTSSGSSSSSQHNHVTRCFGAQQPQQTPPVASSQVPP--VPAASSSSAADRHRE 95
            ||:|...|      .|.|...:...:: |.      ..||| |:..||  :.:.:..:..||:.|
  Rat     8 PPASLPQT------KGKSKRKRDLRIS-CV------SKPPV-SNPTPPRNLDSRTFITIGDRNFE 58

  Fly    96 RIRQQACGKLQFGEGGANTHTFTSDDLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEK 160
                                 ..:|||....|:||||:|.|.|:...:...:|||||||:||:.:
  Rat    59 ---------------------VEADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQ 102

  Fly   161 EQKQLLMDLEVVMKSNECIYIVQFYGALFKEGDCWICMELMDTSLDKFYKYIYEKQQRHIPESIL 225
            |||:|||||::.|::.:|.|.|.||||||:|||.|||||||||||||||:.:.||..: |||.||
  Rat   103 EQKRLLMDLDINMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLEKNMK-IPEDIL 166

  Fly   226 AKITVATVNALNYLKEELKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPYM 290
            .:|.|:.|.||.:|..:|.:|||||||||:|:::.|.:|:|||||||.||||:|||.||||:|||
  Rat   167 GEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYM 231

  Fly   291 APERIDPE-RAKGYDVRSDVWSLGITLMEVATGNFPYRKWDSVFEQLCQVVQGEPPRLLTSYNGM 354
            |||||:|| ..|||:|:|||||||||::|:|...|||..|.:.|:||.|||:...|:|...
  Rat   232 APERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPAD---- 292

  Fly   355 EFSKEFVDFVNTCLIKKESDRPKYSRLLEMPFIRRGETSHTDVAVYVADIL 405
            :||.|||||.:.||.|..::|..|..|:|.||....:|..||:|.:|.:||
  Rat   293 QFSPEFVDFTSQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEIL 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_001163551.1	PKc_MKK4	115..405	CDD:270790	158/290 (54%)
		S_TKc	123..387	CDD:214567	149/264 (56%)
Map2k3	NP_001094144.1	PKc_MKK3_6	62..344	CDD:173729	160/287 (56%)
		S_TKc	67..325	CDD:214567	149/262 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51923
OrthoDB	1	1.010	-	-		D470057at33208
OrthoFinder	1	1.000	-	-		FOG0001217
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101822
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830