Protein Alignment Mkk4 and Map2k5

DIOPT Version :9

• Sequence 1: NP_001163551.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_038936881.1
• Gene: Map2k5 / 29568
• RGDID: 61890
• Length: 487
• Species: Rattus norvegicus
• Alignment Length: 401
• Identity: 142/401 - (35%)
• Similarity: 190/401 - (47%)
• Gaps: 87/401 - (21%)

  Fly     5 PKNLFATGSSRSRNPPDQLSLNNLSIRHPPSSTSSTSSGSTSSGSSSSSQHNHVTRCFGAQQPQQ 69
            |..:|    .|:..||.:.:::.|.:             :|.:|.|                 |.
  Rat   101 PLQIF----PRACKPPGERNIHGLKV-------------NTRAGPS-----------------QH 131

  Fly    70 TPPVASSQVPPVPAASSSSAADRHRERIRQQACGKLQFGEGGANTHTFTSDDLEDEGEIGRGAFG 134
            |.||.|..:|      |:|......|..:..|.|::            ...|:.....:|.|..|
  Rat   132 TSPVVSDSLP------SNSLKKSSAELRKILANGQM------------NEQDIRYRDTLGHGNGG 178

  Fly   135 AVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLEVVMKSNECIYIVQFYGALFKEGDCWICME 199
            .|.|.......|::|||.|...:..:.|||::.:||::.|.:.. ||:.||||.|.|....||.|
  Rat   179 TVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSS-YIIGFYGAFFVENRISICTE 242

  Fly   200 LMD-TSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKEELKIIHRDVKPSNILLHRRGDI 263
            .|| .|||     :|.|    |||.:|.:|.||.|..|.|| ..|||:||||||||:|::..|.:
  Rat   243 FMDGGSLD-----VYRK----IPEHVLGRIAVAVVKGLTYL-WSLKILHRDVKPSNMLVNTSGQV 297

  Fly   264 KLCDFGISGQLVDSIAKTKDAGCRPYMAPERIDPERAKGYDVRSDVWSLGITLMEVATGNFPY-- 326
            ||||||:|.|||:|||||. .|...|||||||..|:   |.:.||||||||:.||:|.|.|||
  Rat   298 KLCDFGVSTQLVNSIAKTY-VGTNAYMAPERISGEQ---YGIHSDVWSLGISFMELALGRFPYPQ 358

  Fly   327 --RKWDSVFE-QLCQ-VVQGEPPRLLTSYNGMEFSKEFVDFV------NTCLIKKES--DRPKYS 379
              :...|:.. ||.| :|..:.|.|...    |||:.||.|:      ..|.....|  .|| |.
  Rat   359 IQKNQGSLMPLQLLQCIVDEDSPVLPLG----EFSEPFVHFITQWNRAGLCRTAHWSLETRP-YR 418

  Fly   380 RLLEMPFIRRG 390
            ..|:.||..||
  Rat   419 FTLKKPFSTRG 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_001163551.1	PKc_MKK4	115..405	CDD:270790	122/291 (42%)
		S_TKc	123..387	CDD:214567	118/278 (42%)
Map2k5	XP_038936881.1	PB1_Map2k5	17..107	CDD:99717	2/9 (22%)
		PKc_like	164..401	CDD:419665	112/255 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D688282at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920