Protein Alignment Mkk4 and sek-6

DIOPT Version :9

• Sequence 1: NP_001163551.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_509683.1
• Gene: sek-6 / 189074
• WormBaseID: WBGene00012162
• Length: 359
• Species: Caenorhabditis elegans
• Alignment Length: 331
• Identity: 143/331 - (43%)
• Similarity: 201/331 - (60%)
• Gaps: 4/331 - (1%)

  Fly    67 PQQTPPVASSQVPPVPAASSSSAADRHRERIRQQACGKLQFGEGGANTHTFTSDDLEDEGEIGRG 131
            |....||..:..|.:.:.||:..:......:|..:.|.|:|.: .|:.:.|...:|....::|.|
 Worm    10 PMFARPVFLANRPTLESLSSNDGSVAEENPLRSMSTGILKFPD-DAHLYPFNHTNLRHLSQVGAG 73

  Fly   132 AFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLEVVMKSNECIYIVQFYGALFKEGDCWI 196
            .:|.|:||...:..:::|||:||.. :..:|.:||.:.:..|||.....||:|:||.|.||||||
 Worm    74 YYGTVHKMQHNESGRLIAVKKIRYN-NICDQTRLLKEHDTHMKSENVPNIVKFFGACFSEGDCWI 137

  Fly   197 CMELMDTSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKEELKIIHRDVKPSNILLHRRG 261
            ||||||.|:|..||.:|..::..:.|:|:..|||..|:||:|||.:|..|||||||||||::..|
 Worm   138 CMELMDISIDFLYKRVYSVKKSRLNENIIGHITVCIVDALDYLKRKLNRIHRDVKPSNILINAAG 202

  Fly   262 DIKLCDFGISGQLVDSIAKTKDAGCRPYMAPERIDPERAKGYDVRSDVWSLGITLMEVATGNFPY 326
            |:|||||||.|.||.|.|.|.:|||..|:|||||  |....||:|||||||||||.|:|||.:||
 Worm   203 DVKLCDFGICGDLVGSYAITVEAGCVQYLAPERI--ENMDKYDIRSDVWSLGITLYEIATGVYPY 265

  Fly   327 RKWDSVFEQLCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIKKESDRPKYSRLLEMPFIRRGE 391
            |.|.:..|.:..||.|:.|.||.:.:.:.::.....|:||||.|.:.|||||..|....|.:...
 Worm   266 RGWSNQMEHIEIVVNGDSPILLQNMHNLHYTDPLCRFINTCLRKNKDDRPKYVNLKTFSFYKMYA 330

  Fly   392 TSHTDV 397
            ....|:
 Worm   331 VGGPDI 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_001163551.1	PKc_MKK4	115..405	CDD:270790	132/283 (47%)
		S_TKc	123..387	CDD:214567	128/263 (49%)
sek-6	NP_509683.1	PKc_like	57..343	CDD:389743	132/283 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166760
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1006
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	302	1.000	Inparanoid score	I1612
Isobase	1	0.950	-	0	Normalized mean entropy	S1132
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D470057at33208
OrthoFinder	1	1.000	-	-		FOG0001217
OrthoInspector	1	1.000	-	-		otm14198
orthoMCL	1	0.900	-	-		OOG6_101822
Panther	1	1.100	-	-	O	PTHR48013
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3433
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.710